Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 6/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14275635 | 1.00 | ADRA2A (0.50) | ADRA2AADRA2BADRA1AMAP3K14SLC6A2 | |
| SCHEMBL1266132 | 0.82 | ADRA2A (0.50) | ADRA2AADRA2BADRA1AHTR2CHTR2B | |
| SCHEMBL1265344 | 0.82 | ADRA2A (0.50) | ADRA2AADRA2BADRA1AHTR2CHTR2B | |
| SCHEMBL1265342 | 0.82 | ADRA2A (0.50) | ADRA2AADRA2BADRA1AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL1266175 | 0.81 | ADRA2A (0.49) | ADRA2AADRA2BADRA1AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL30563578 | 0.81 | ADRA2A (0.49) | ADRA2AADRA2BADRA1AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL1266173 | 0.81 | ADRA2A (0.49) | ADRA2AADRA2BADRA1AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL26962833 | 0.81 | ADRA2A (0.49) | ADRA2AADRA2BADRA1AHTR2CHTR2B | |
| SCHEMBL11981386 | 0.80 | ADRA2A (0.51) | ADRA2AADRA2BADRA1AMAP3K14HTR2C | |
| SCHEMBL16509662 | 0.80 | ADRA2A (0.51) | ADRA2AADRA2BADRA1AMAP3K14HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743453-A1 | MODULATORS OF MITOCHONDRIAL DNA REPLICATION | Pretzel Therapeutics, Inc. (US) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025015178-A1 | MODULATORS OF MITOCHONDRIAL DNA REPLICATION | PRETZEL THERAPEUTICS, INC. (US) | 2025-01-16 | — | — | WO | disclosed |