Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 9/20 | 0.63 |
| ▸ | CYP11B2 | P19099 | 9/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.54 |
| ▸ | PIP4K2B | P78356 | 1/20 | 0.54 |
| ▸ | FYN | P06241 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAP3K11 | Q16584 | 3/20 | 0.48 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.48 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.47 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.47 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7089083 | 0.81 | NPC1 (0.62) | CYP11B1CYP11B2NPC1CYP17A1DYRK3 | |
| SCHEMBL31504069 | 0.80 | NPC1 (0.62) | CYP1A2CYP3A4CYP2C9NPC1 | |
| SCHEMBL13354456 | 0.80 | PIP4K2A (0.58) | CYP11B1CYP11B2PIP4K2APIP4K2BFYN | |
| SCHEMBL29652336 | 0.79 | BRD4 (0.62) | CYP11B1CYP11B2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10081083 | 0.79 | PIK3CG (0.57) | PIP4K2APIP4K2BNPC1PRKCQ | |
| SCHEMBL3004402 | 0.78 | CYP11B2 (1.00) | CYP11B1CYP11B2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3348627 | 0.77 | PIP4K2A (0.54) | CYP11B1CYP11B2PIP4K2APIP4K2BFYN | |
| SCHEMBL13322392 | 0.77 | PIP4K2A (0.54) | CYP11B1CYP11B2PIP4K2APIP4K2BFYN | |
| SCHEMBL731092 | 0.77 | NPC1 (0.49) | CYP11B1CYP11B2NPC1MAP3K11PRKCQ | |
| SCHEMBL7413835 | 0.76 | CYP11B2 (0.78) | CYP11B1CYP11B2CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119212698-A | NOX inhibitors for the treatment of Albert syndrome | 瑞士商卡利迪塔斯疗法瑞士股份有限公司 | 2024-12-27 | — | — | CN | claimed |
| CN-119212698-A | NOX inhibitors for the treatment of Albert syndrome | 瑞士商卡利迪塔斯疗法瑞士股份有限公司 | 2024-12-27 | — | — | CN | disclosed |