Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 9/20 | 0.37 |
| ▸ | BCR | P11274 | 9/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.37 |
| ▸ | CNR1 | P21554 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29097717 | 0.83 | HCRTR2 (0.37) | HCRTR2SMN1; SMN2ABL1BCRHDAC3 | |
| SCHEMBL30621978 | 0.83 | HCRTR2 (0.37) | HCRTR2SMN1; SMN2ABL1BCRHDAC3 | |
| SCHEMBL30621967 | 0.76 | PTPN11 (0.46) | SMN1; SMN2 | |
| SCHEMBL29097712 | 0.76 | PTPN11 (0.46) | SMN1; SMN2 | |
| SCHEMBL29097721 | 0.76 | HCRTR2 (0.38) | HCRTR2SMN1; SMN2ABL1BCRMAPT | |
| SCHEMBL29097714 | 0.76 | ABL1 (0.39) | HCRTR2SMN1; SMN2ABL1BCRCNR1 | |
| SCHEMBL30621965 | 0.76 | ABL1 (0.39) | HCRTR2SMN1; SMN2ABL1BCRCNR1 | |
| SCHEMBL23063935 | 0.76 | PTPN11 (0.38) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL20137707 | 0.74 | PANK3 (0.43) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL20399762 | 0.72 | HDAC3 (0.33) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025011447-A1 | PYRIMIDINAMINE NUAK INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 特科罗生物科技(成都)有限公司 | 2025-01-16 | — | — | WO | disclosed |