Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 3/20 | 0.34 |
| ▸ | PIM1 | P11309 | 2/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.32 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26097180 | 0.81 | CYP2A6 (0.41) | CYP2A6KMT2APIM3PIM1PIM2 | |
| SCHEMBL21954726 | 0.78 | LRRK2 (0.38) | CCNT1CDK9LRRK2CHEK1MAPK1 | |
| SCHEMBL15359645 | 0.75 | CHEK1 (0.36) | CCNT1CDK9LRRK2CHEK1MAPK1 | |
| SCHEMBL2112465 | 0.75 | CHEK1 (0.51) | LRRK2CHEK1MAPK1 | |
| SCHEMBL29952411 | 0.74 | CYP2A6 (0.41) | CYP2A6KMT2APIM3PIM1PIM2 | |
| SCHEMBL25088414 | 0.74 | MAP4K1 (0.46) | LRRK2CHEK1MAPK1 | |
| SCHEMBL30217625 | 0.74 | MAP4K1 (0.46) | LRRK2CHEK1MAPK1 | |
| SCHEMBL672053 | 0.73 | CYP2A6 (0.51) | CYP2A6KMT2APIM3PIM1PIM2 | |
| SCHEMBL30735475 | 0.73 | PRKAG1 (0.38) | — | |
| SCHEMBL16854295 | 0.72 | CHEK1 (0.49) | KMT2ACHEK1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118894852-A | Polysubstituted indazole compound and preparation method and application thereof | 甫康（上海）健康科技有限责任公司 | 2024-11-05 | — | — | CN | disclosed |