Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | S100A4 | P26447 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31318416 | 0.84 | MAOB (0.48) | ALDH1A1KMT2AMEN1ADORA2APPARG | |
| SCHEMBL28346611 | 0.78 | PTGS2 (0.41) | L3MBTL1KDM4EALDH1A1TSHRNPSR1 | |
| SCHEMBL28310257 | 0.75 | MAOB (0.50) | KDM4EALDH1A1KMT2AMEN1PPARG | |
| SCHEMBL5886326 | 0.74 | CYP2A6 (0.44) | L3MBTL1KDM4EALDH1A1TSHRMRGPRX4 | |
| SCHEMBL27036826 | 0.72 | HTT (0.40) | L3MBTL1KDM4EALDH1A1NPSR1KMT2A | |
| SCHEMBL31460521 | 0.71 | KDM4E (0.41) | L3MBTL1KDM4EALDH1A1TSHRNPSR1 | |
| SCHEMBL22531485 | 0.71 | KDM4E (0.41) | L3MBTL1KDM4EALDH1A1TSHRNPSR1 | |
| SCHEMBL6366697 | 0.71 | POLB (0.52) | L3MBTL1KDM4EALDH1A1NPSR1KMT2A | |
| SCHEMBL28041457 | 0.71 | MAOA (0.56) | KDM4ETSHRMRGPRX4KMT2AMEN1 | |
| SCHEMBL7587251 | 0.71 | PARP10 (0.54) | MRGPRX4KMT2AMEN1MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119285479-A | Preparation and application of novel MAO-B inhibitor containing tetrahydronaphthalene-1-amine structure | 重庆医科大学 | 2025-01-10 | — | — | CN | disclosed |