SCHEMBL3131841

SCHEMBL3131841

CCCC(CCC(=O)O)(c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 15/20 0.72
ESR2 Q92731 8/20 0.72
ALDH1A1 P00352 1/20 0.62
CYP3A4 P08684 1/20 0.62
AR P10275 1/20 0.47
CHEK1 O14757 1/20 0.42
FYN P06241 1/20 0.42
PDGFRB P09619 1/20 0.42
PIM1 P11309 1/20 0.42
FGFR1 P11362 1/20 0.42
FLT1 P17948 1/20 0.42
GRK5 P34947 1/20 0.42
MAP2K2 P36507 1/20 0.42
MAPK8 P45983 1/20 0.42
CDK8 P49336 1/20 0.42
RPS6KA3 P51812 1/20 0.42
PRKX P51817 1/20 0.42
JAK3 P52333 1/20 0.42
LIMK1 P53667 1/20 0.42
BTK Q06187 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL656272 0.90 ESR1 (0.74) ESR1ESR2ALDH1A1CYP3A4CHEK1
SCHEMBL3693611 0.88 ESR1 (0.64) ESR1ESR2ALDH1A1CYP3A4AR
SCHEMBL3471623 0.87 ESR1 (0.65) ESR1ESR2ALDH1A1CYP3A4HSD17B3
SCHEMBL3470640 0.87 ESR1 (0.65) ESR1ESR2ALDH1A1CYP3A4HSD17B3
SCHEMBL3471552 0.87 ESR1 (0.65) ESR1ESR2ALDH1A1CYP3A4HSD17B3
SCHEMBL272801 0.85 ESR1 (1.00) ESR1ESR2CYP3A4AR
SCHEMBL51339 0.84 ESR1 (0.69) ESR1ESR2ALDH1A1CYP3A4AR
SCHEMBL28036387 0.82 ESR1 (0.84) ESR1ESR2ALDH1A1CYP3A4AR
SCHEMBL3471117 0.80 ESR1 (0.51) ESR1ESR2ALDH1A1CYP3A4HSD17B3
SCHEMBL3120824 0.80 ESR1 (0.58) ESR1ESR2ALDH1A1CYP3A4AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5668080-A SHEET COATED WITH COLOR-FORMING SYSTEM COMPRISING CHROMOGENIC MATERIAL, ACIDIC DEVELOPER, ALPHA-/TRICHLOROMETHYL/-BENZYL ACETATE; IMPROVED IMAGE STABILITY APPLETON PAPERS INC. (US) 1997-09-16 US claimed
EP-0545525-B1 Thermally-responsive record material APPLETON PAPER INC (US) 1996-01-03 EP claimed
EP-0414509-B1 Heat sensitive record material APPLETON PAPER INC (US) 1994-09-21 EP claimed
EP-0545525-A1 Thermally-responsive record material APPLETON PAPERS INC. (US) 1993-06-09 EP claimed
US-5164356-A Image stability, zinc stearate/ammonia complex APPLETON PAPERS INC. (US) 1992-11-17 US claimed
US-4895827-A Containing cinnamic metal salt APPLETON PAPERS INC. (US) 1990-01-23 US claimed
EP-0161105-B1 RECORD MATERIAL APPLETON PAPERS INC. (US) 1989-12-20 EP claimed
US-4870047-A RESISTANCE TO FADING OR ERASURE APPLETON PAPERS INC. (US) 1989-09-26 US claimed
US-4820683-A COLORFASTNESS APPLETON PAPERS INC. (US) 1989-04-11 US claimed
US-4535347-A HYDROXYANILIDES, PHENOLIC DEVELOPERS, CHROMOGENIC COMPOUNDS; BLOOMRESISTANCE APPLETON PAPERS INC. (US) 1985-08-13 US claimed
US-4470057-A CHROMOGENIC COMPOUND, ACIDIC DEVELOPERS, AND PHENYLHYDROXYNAPHTHOATE APPLETON PAPERS INC. (US) 1984-09-04 US claimed
EP-3194176-B1 LINERLESS RECORD MATERIAL APPVION LLC (US) 2022-09-14 EP disclosed
US-11292280-B2 Printable and scuff resistant silicone release coating for linerless thermally-responsive record material APPVION OPERATIONS, INC. (US) 2022-04-05 US disclosed
US-20190193447-A1 PRINTABLE AND SCUFF RESISTANT SILICONE RELEASE COATING FOR LINERLESS THERMALLY-RESPONSIVE RECORD MATERIAL WC APV OPCO, LLC 2019-06-27 US disclosed
US-20170340955-A1 THERMALLY IMAGEABLE SUBSTRATE WITH ENCAPSULATED COREACTANT APPVION OPERATIONS, INC. 2017-11-30 US disclosed
US-4870047-A RESISTANCE TO FADING OR ERASURE APPLETON PAPERS INC. (US) 1989-09-26 US disclosed
US-4820683-A COLORFASTNESS APPLETON PAPERS INC. (US) 1989-04-11 US disclosed
US-4794102-A RESISTANCE TO IMAGE ERASURE APPLETON PAPERS INC. (US) 1988-12-27 US disclosed
US-4535347-A HYDROXYANILIDES, PHENOLIC DEVELOPERS, CHROMOGENIC COMPOUNDS; BLOOMRESISTANCE APPLETON PAPERS INC. (US) 1985-08-13 US disclosed
US-4470057-A CHROMOGENIC COMPOUND, ACIDIC DEVELOPERS, AND PHENYLHYDROXYNAPHTHOATE APPLETON PAPERS INC. (US) 1984-09-04 US disclosed