Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 4/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21837048 | 1.00 | TPMT (0.67) | TPMTHSD17B10KMT2AALDH1A1KDM4E | |
| SCHEMBL1191343 | 0.87 | TPMT (0.79) | TPMTHSD17B10KMT2AALDH1A1KDM4E | |
| SCHEMBL3546802 | 0.87 | TPMT (0.79) | TPMTHSD17B10KMT2AALDH1A1HTT | |
| SCHEMBL31573601 | 0.84 | ALDH1A1 (0.51) | TPMTALDH1A1KDM4EGAAHTT | |
| SCHEMBL21836913 | 0.84 | ALDH1A1 (0.51) | TPMTALDH1A1KDM4EGAAHTT | |
| SCHEMBL1204414 | 0.80 | HTT (0.72) | TPMTHSD17B10KMT2AALDH1A1HTT | |
| SCHEMBL21880315 | 0.80 | TPMT (0.69) | TPMTHSD17B10KMT2AALDH1A1KDM4E | |
| SCHEMBL30740894 | 0.80 | HTT (0.72) | TPMTHSD17B10KMT2AALDH1A1HTT | |
| SCHEMBL985914 | 0.80 | TPMT (0.69) | TPMTALDH1A1KDM4EGAAHTT | |
| SCHEMBL4831712 | 0.79 | ALDH1A1 (0.58) | TPMTHSD17B10KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119059989-A | URAT1 inhibitor, preparation method and application thereof | 中国药科大学 | 2024-12-03 | — | — | CN | disclosed |