SCHEMBL3546802

SCHEMBL3546802

COc1c(Br)cc(C(=O)O)cc1Br

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TPMT P51580 5/20 0.79
HSD17B10 Q99714 1/20 0.58
KMT2A Q03164 1/20 0.57
TTR P02766 1/20 0.56
TSHR P16473 1/20 0.55
APOBEC3A P31941 1/20 0.55
HTT P42858 1/20 0.55
APOBEC3G Q9HC16 1/20 0.55
THRA P10827 2/20 0.50
THRB P10828 2/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA3 P07451 1/20 0.50
PKM P14618 1/20 0.50
CA4 P22748 1/20 0.50
CA6 P23280 1/20 0.50
CA5A P35218 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1204414 0.88 HTT (0.72) TPMTHSD17B10KMT2ATSHRAPOBEC3A
SCHEMBL30740894 0.88 HTT (0.72) TPMTHSD17B10KMT2ATSHRAPOBEC3A
SCHEMBL31063258 0.87 TPMT (0.67) TPMTHSD17B10KMT2ATTRTSHR
SCHEMBL29198878 0.87 TPMT (0.67) TPMTHSD17B10KMT2ATTRTSHR
SCHEMBL21837048 0.87 TPMT (0.67) TPMTHSD17B10KMT2ATTRTSHR
SCHEMBL1560980 0.87 TPMT (0.67) TPMTHSD17B10KMT2ATTRTSHR
SCHEMBL31318522 0.87 TPMT (0.67) TPMTHSD17B10KMT2ATTRTSHR
SCHEMBL7670073 0.85 TPMT (0.65) TPMTHSD17B10KMT2ATTRTSHR
SCHEMBL1302354 0.84 TPMT (0.63) TPMTHSD17B10KMT2ATTRTSHR
SCHEMBL31318546 0.82 TPMT (0.61) TPMTHSD17B10KMT2ATTRTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113943228-B Alkaloid pulmonin B derivative, synthesis thereof and application thereof in preventing and treating plant virus and germ diseases 天津师范大学 2023-10-27 CN claimed
US-20260070923-A1 METHOD FOR PREPARING HETEROCYCLIC DERIVATIVE COMPOUND, COMPOSITION CONTAINING SAME COMPOUND, AND HYDRATE OF SAME COMPOUND JW PHARMACEUTICAL CORP (KR) 2026-03-12 US disclosed
US-12497410-B2 Method for preparing heterocyclic derivative compound, composition containing same compound, and hydrate of same compound JW PHARMACEUTICAL CORPORATION (KR) 2025-12-16 US disclosed
WO-2025224674-A1 ALICHONDRICHLORIN FOR USE IN TREATING CANCER CIIMAR - CENTRO INTERDISCIPLINAR DE INVESTIGAÇÃO MARINHA E AMBIENTAL (PT) 2025-10-30 WO disclosed
CN-119143779-A Process for preparing heterocyclic derivative compounds, compositions containing the compounds and hydrates of the compounds JW 制药公司 2024-12-17 CN disclosed
EP-3909956-B1 HYDROCHLORIDE SALT 1.5 HYDRATE OF AN HETEROCYCLIC DERIVATIVE COMPOUND JW PHARMACEUTICAL CORP (KR) 2024-12-04 EP disclosed
CN-119059989-A URAT1 inhibitor, preparation method and application thereof 中国药科大学 2024-12-03 CN disclosed
US-12103938-B2 Method for preparing heterocyclic derivative compound, composition containing same compound, and hydrate of same compound JW PHARMACEUTICAL CORPORATION (KR) 2024-10-01 US disclosed
CN-114085235-B Process for preparing heterocyclic derivative compounds, compositions containing the compounds and hydrates of the compounds JW 制药公司 2024-08-13 CN disclosed
US-12030895-B2 Method for preparing heterocyclic derivative compound, composition containing same compound, and hydrate of same compound JW PHARMACEUTICAL CORPORATION (KR) 2024-07-09 US disclosed
EP-1091958-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2001-04-18 EP disclosed
EP-1077969-A1 BENZOTHIOPHENES, BENZOFURANS, AND INDOLES USEFUL IN THE TREATMENT OF INSULIN RESISTANCE AND HYPERGLYCEMIA AMERICAN HOME PRODUCTS CORPORATION (US) 2001-02-28 EP disclosed
WO-2000001692-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2000-01-13 WO disclosed
WO-1999061435-A1 BENZOTHIOPHENES, BENZOFURANS, AND INDOLES USEFUL IN THE TREATMENT OF INSULIN RESISTANCE AND HYPERGLYCEMIA AMERICAN HOME PRODUCTS CORPORATION (US) 1999-12-02 WO disclosed
US-5861416-A TREATMENT OF ASTHMA OR COUGH MERRELL PHARMACEUTICALS INC. (US) 1999-01-19 US disclosed
US-5824690-A TREATING ASTHMA, COUGH HOECHST MARION ROUSSEL INC. (US) 1998-10-20 US disclosed
US-5661160-A ADMINISTERING AN ANTITUSSIVE AGENT FOR TREATING COUGH; TACHYKININ ANTAGONISM, SUBSTANCE P AND NEUROKININ A ANTAGONISM MERRELL PHARMACEUTICALS INC. (US) 1997-08-26 US disclosed
US-5648366-A TACHYKININ ANTAGONISTS USEFUL IN TREATING ASTHMA MERRELL PHARMACEUTICALS INC. (US) 1997-07-15 US disclosed
US-5635510-A TACHYKININ (ESPECIALLY SUBSTANCE P AND NEUROKININ A) ANTAGONISTS; ANTIINFLAMMATORY AGENTS, ANALGESICS; NERVOUS SYSTEM DISORDERS; BRONCHODILATOR AGENTS MERRELL PHARMACEUTICALS INC. (US) 1997-06-03 US disclosed
US-4274998-A Diester of 3,5,3',5'-tetrabromo-bisphenol A with halogenated aromatic carboxylic acid ASAHI-DOW LIMITED (JP) 1981-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12103938-B2 Method for preparing heterocyclic derivative compound, composition containing same compound, and hydrate of same compound REN, NOD1, NLRP3 TPMT 187/4885HSD17B10 1328/4885KMT2A 2874/4885
US-20260070923-A1 METHOD FOR PREPARING HETEROCYCLIC DERIVATIVE COMPOUND, COMPOSITION CONTAINING SAME COMPOUND, AND HYDRATE OF SAME COMPOUND SLC26A3, SLC10A6, SLC14A1 TPMT 120/4885HSD17B10 441/4885KMT2A 2561/4885
US-12497410-B2 Method for preparing heterocyclic derivative compound, composition containing same compound, and hydrate of same compound REN, NOD1, NLRP3 TPMT 187/4885HSD17B10 1328/4885KMT2A 2874/4885
US-12030895-B2 Method for preparing heterocyclic derivative compound, composition containing same compound, and hydrate of same compound REN, NOD1, NLRP3 TPMT 187/4885HSD17B10 1328/4885KMT2A 2874/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.