Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | COMT | P21964 | 1/20 | 0.31 |
| ▸ | SPR | P35270 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31318570 | 0.87 | PDE4B (0.39) | ACACBSMN1; SMN2ALDH1A1RORC | |
| SCHEMBL31318542 | 0.87 | SLC22A12 (0.44) | SLC22A12CYP2C9 | |
| SCHEMBL31318512 | 0.87 | SLC22A12 (0.44) | SLC22A12ACACBSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL31318516 | 0.81 | SLC22A12 (0.43) | SLC22A12ALDH1A1CYP2C9GPBAR1 | |
| SCHEMBL31318492 | 0.79 | MEN1 (0.40) | SLC22A12SMN1; SMN2ALDH1A1CYP2C9 | |
| SCHEMBL31318545 | 0.79 | TUBB4A (0.39) | SLC22A12ALDH1A1TSHRCYP2C19 | |
| SCHEMBL31318520 | 0.79 | MEN1 (0.36) | SLC22A12ALDH1A1CYP2C9CYP3A4GPBAR1 | |
| SCHEMBL31318557 | 0.78 | SLC22A12 (0.48) | SLC22A12CYP2D6SMN1; SMN2CYP3A4CYP2C19 | |
| SCHEMBL31318563 | 0.74 | SLC22A12 (0.39) | SLC22A12ALDH1A1HPGDTSHR | |
| SCHEMBL31318571 | 0.70 | NR3C2 (0.38) | SLC22A12ALDH1A1TSHRUSP2GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119059989-A | URAT1 inhibitor, preparation method and application thereof | 中国药科大学 | 2024-12-03 | — | — | CN | disclosed |