Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31318550 | 0.90 | ALDH1A1 (0.38) | MEN1KMT2AMAPTSLC22A12LMNA | |
| SCHEMBL31318570 | 0.88 | PDE4B (0.39) | MAPTTP53LMNACDK5CDK5R1 | |
| SCHEMBL31318545 | 0.88 | TUBB4A (0.39) | MAPTSLC22A12TP53LMNACDK5 | |
| SCHEMBL31318542 | 0.87 | SLC22A12 (0.44) | SLC22A12TP53CYP2C9 | |
| SCHEMBL31318517 | 0.83 | SIRT3 (0.41) | MEN1KMT2ASLC22A12TAS1R3TAS1R1 | |
| SCHEMBL31318492 | 0.80 | MEN1 (0.40) | MEN1KMT2AMAPTSLC22A12LMNA | |
| SCHEMBL31318501 | 0.80 | SLC22A12 (0.41) | MEN1RAB9AKMT2ASLC22A12TAS1R3 | |
| SCHEMBL31318512 | 0.79 | SLC22A12 (0.44) | MEN1KMT2AMAPTSLC22A12TP53 | |
| SCHEMBL31318524 | 0.79 | SLC22A12 (0.38) | SLC22A12GPBAR1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL31318491 | 0.76 | TUBB4A (0.43) | MEN1RAB9AKMT2AMAPTSLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119059989-A | URAT1 inhibitor, preparation method and application thereof | 中国药科大学 | 2024-12-03 | — | — | CN | disclosed |