Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 8/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31318531 | 0.87 | LMNA (0.38) | SLC22A12ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL31318497 | 0.86 | SLC22A12 (0.40) | SLC22A12CYP2C9ABCG2GAAALDH1A1 | |
| SCHEMBL31318561 | 0.86 | SLC22A12 (0.48) | SLC22A12CYP2C9ABCG2MEN1KMT2A | |
| SCHEMBL31318549 | 0.78 | SLC22A12 (0.39) | SLC22A12CYP2C9ABCG2GAAHTT | |
| SCHEMBL31318565 | 0.78 | LMNA (0.40) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL31318516 | 0.74 | SLC22A12 (0.43) | SLC22A12CYP2C9ABCG2GAAHTT | |
| SCHEMBL4900194 | 0.67 | POLB (0.62) | SLC22A12GPBAR1LMNANOTUM | |
| SCHEMBL31318524 | 0.66 | SLC22A12 (0.38) | SLC22A12CYP2C9GPBAR1ALDH1A1MAPK1 | |
| SCHEMBL10322736 | 0.65 | SLC22A12 (0.84) | SLC22A12CYP2C9ABCG2GAAHTT | |
| SCHEMBL31318563 | 0.64 | SLC22A12 (0.39) | SLC22A12GAAHTTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119059989-A | URAT1 inhibitor, preparation method and application thereof | 中国药科大学 | 2024-12-03 | — | — | CN | disclosed |