Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 11/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31318513 | 0.88 | MEN1 (0.42) | SLC22A12ABCG2CYP2C9POLB | |
| SCHEMBL31318517 | 0.86 | SIRT3 (0.41) | SLC22A12ABCG2CYP2C9POLBHSD11B1 | |
| SCHEMBL31318523 | 0.85 | SLC22A12 (0.44) | SLC22A12ABCG2CYP2C9POLBSIRT1 | |
| SCHEMBL31318504 | 0.85 | SLC22A12 (0.42) | SLC22A12ABCG2CYP2C9POLBSIRT1 | |
| SCHEMBL31318516 | 0.85 | SLC22A12 (0.43) | SLC22A12ABCG2CYP2C9POLBSIRT1 | |
| SCHEMBL31318569 | 0.85 | SLC22A12 (0.55) | SLC22A12ABCG2CYP2C9SLC22A6 | |
| SCHEMBL31318506 | 0.84 | SLC22A12 (0.48) | SLC22A12ABCG2CYP2C9SLC22A6 | |
| SCHEMBL31318547 | 0.82 | SLC22A12 (0.39) | SLC22A12ABCG2CYP2C9POLB | |
| SCHEMBL31318542 | 0.81 | SLC22A12 (0.44) | SLC22A12ABCG2CYP2C9HSD11B1SLC22A6 | |
| SCHEMBL31318571 | 0.79 | NR3C2 (0.38) | SLC22A12POLBSIRT1HSD11B1SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119059989-A | URAT1 inhibitor, preparation method and application thereof | 中国药科大学 | 2024-12-03 | — | — | CN | disclosed |