Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 6/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.34 |
| ▸ | JUN | P05412 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | MAT2A | P31153 | 1/20 | 0.33 |
| ▸ | RHOC | P08134 | 1/20 | 0.33 |
| ▸ | RHOA | P61586 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31318536 | 0.88 | CYP3A4 (0.37) | CYP2C9EPHX2EPHX1HCRTR2MRGPRX4 | |
| SCHEMBL31318508 | 0.87 | SLC22A12 (0.40) | SLC22A12CYP2C9EPHX2EPHX1TRPM8 | |
| SCHEMBL31318539 | 0.82 | SLC22A12 (0.50) | SLC22A12CYP2C9ABCG2POLB | |
| SCHEMBL31318507 | 0.80 | TUBB4A (0.37) | CYP2C9EPHX2EPHX1TRPM8 | |
| SCHEMBL4901585 | 0.79 | SLC22A12 (0.47) | SLC22A12CYP2C9ABCG2HCRTR2MAT2A | |
| SCHEMBL31318506 | 0.78 | SLC22A12 (0.48) | SLC22A12CYP2C9ABCG2 | |
| SCHEMBL31318569 | 0.77 | SLC22A12 (0.55) | SLC22A12CYP2C9ABCG2 | |
| SCHEMBL31318577 | 0.76 | TTR (0.36) | SLC22A12CYP2C9ABCG2NFKB1TP53 | |
| SCHEMBL31318515 | 0.74 | SLC22A12 (0.44) | SLC22A12CYP2C9ABCG2 | |
| SCHEMBL31318542 | 0.74 | SLC22A12 (0.44) | SLC22A12CYP2C9ABCG2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119059989-A | URAT1 inhibitor, preparation method and application thereof | 中国药科大学 | 2024-12-03 | — | — | CN | disclosed |