Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 7/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31318539 | 0.88 | SLC22A12 (0.50) | SLC22A12CYP2C9ABCG2POLB | |
| SCHEMBL31318577 | 0.87 | TTR (0.36) | MEN1KMT2ASLC22A12CYP2C9ABCG2 | |
| SCHEMBL31318498 | 0.87 | SLC22A12 (0.44) | MEN1KMT2ASLC22A12CYP2C9ABCG2 | |
| SCHEMBL31318548 | 0.87 | ALDH1A1 (0.40) | MEN1KMT2ASLC22A12SMN1; SMN2L3MBTL1 | |
| SCHEMBL31318532 | 0.87 | SLC22A12 (0.42) | MEN1KMT2ASLC22A12CYP2C9ABCG2 | |
| SCHEMBL31318492 | 0.85 | MEN1 (0.40) | MEN1KMT2ASLC22A12CYP2C9ABCG2 | |
| SCHEMBL4902036 | 0.81 | POLB (0.58) | MEN1KMT2ASLC22A12CYP2C9ABCG2 | |
| SCHEMBL31318517 | 0.78 | SIRT3 (0.41) | MEN1KMT2ASLC22A12CYP2C9ABCG2 | |
| SCHEMBL31318504 | 0.77 | SLC22A12 (0.42) | KMT2ASLC22A12CYP2C9ABCG2ALDH1A1 | |
| SCHEMBL31318516 | 0.77 | SLC22A12 (0.43) | KMT2ASLC22A12CYP2C9ABCG2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119059989-A | URAT1 inhibitor, preparation method and application thereof | 中国药科大学 | 2024-12-03 | — | — | CN | disclosed |