Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31318535 | 0.93 | SLC22A12 (0.38) | SLC22A6SLC22A8SLC22A12ROCK2 | |
| SCHEMBL31318501 | 0.88 | SLC22A12 (0.41) | SLC22A6SLC22A8SLC22A12TDP1LMNA | |
| SCHEMBL31318505 | 0.88 | SLC22A6 (0.50) | SLC22A6SLC22A8SLC22A12TDP1HTT | |
| SCHEMBL31318557 | 0.87 | SLC22A12 (0.48) | SLC22A6SLC22A8SLC22A12CYP11B2CYP3A4 | |
| SCHEMBL31318544 | 0.85 | SIRT3 (0.41) | SLC22A12LMNATSHR | |
| SCHEMBL31318541 | 0.84 | SLC22A12 (0.46) | SLC22A6SLC22A8SLC22A12HTTGPBAR1 | |
| SCHEMBL31318515 | 0.83 | SLC22A12 (0.44) | SLC22A6SLC22A8SLC22A12 | |
| SCHEMBL31318552 | 0.80 | TUBB4A (0.43) | SLC22A12HTTLMNATSHR | |
| SCHEMBL1190333 | 0.80 | SLC22A12 (0.64) | SLC22A6SLC22A8SLC22A12GPBAR1LMNA | |
| SCHEMBL31318570 | 0.80 | PDE4B (0.39) | PDE4BPDE4DLMNAPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119059989-A | URAT1 inhibitor, preparation method and application thereof | 中国药科大学 | 2024-12-03 | — | — | CN | disclosed |