Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.37 |
| ▸ | TUBB | P07437 | 2/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.37 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.37 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.37 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31318572 | 0.87 | ATM (0.44) | SIRT3LMNASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL31318560 | 0.87 | SIRT3 (0.41) | SIRT3LMNASMN1; SMN2TUBB4ATUBB | |
| SCHEMBL31318493 | 0.87 | LMNA (0.42) | SIRT3LMNASMN1; SMN2TUBB4ATUBB | |
| SCHEMBL31318517 | 0.87 | SIRT3 (0.41) | SIRT3LMNATUBB4ATUBBTUBA3C | |
| SCHEMBL31318516 | 0.86 | SLC22A12 (0.43) | SIRT3LMNAKMT2AALDH1A1SLC22A12 | |
| SCHEMBL31318552 | 0.86 | TUBB4A (0.43) | SIRT3LMNATUBB4ATUBBTUBA3C | |
| SCHEMBL31318558 | 0.85 | SLC22A6 (0.41) | LMNATSHRSLC22A12 | |
| SCHEMBL31318570 | 0.83 | PDE4B (0.39) | LMNASMN1; SMN2TUBB4ATUBBTUBA3C | |
| SCHEMBL31318571 | 0.82 | NR3C2 (0.38) | SIRT3LMNATSHRALDH1A1SLC22A12 | |
| SCHEMBL31318504 | 0.79 | SLC22A12 (0.42) | SIRT3LMNAKMT2AALDH1A1SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119059989-A | URAT1 inhibitor, preparation method and application thereof | 中国药科大学 | 2024-12-03 | — | — | CN | disclosed |