Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31319820 | 0.78 | IDO1 (0.38) | MAP3K14PIK3CAMTORADORA2AFLT3 | |
| SCHEMBL31319864 | 0.74 | TSHR (0.45) | TSHR | |
| SCHEMBL18766664 | 0.74 | IDO1 (0.47) | MAP3K14PIK3CAMTORFLT3HPGD | |
| SCHEMBL23985294 | 0.73 | TGFBR1 (0.44) | MAP3K14PIK3CAMTORADORA2ATGFBR1 | |
| SCHEMBL17338963 | 0.73 | PIK3CA (0.43) | MAP3K14PIK3CAMTORADORA2ATGFBR1 | |
| SCHEMBL18766678 | 0.70 | HRH3 (0.39) | MAP3K14PIK3CAMTOR | |
| SCHEMBL18766613 | 0.70 | TGFBR1 (0.40) | MAP3K14PIK3CAMTORTGFBR1FLT3 | |
| SCHEMBL18766621 | 0.68 | ALDH1A1 (0.48) | PIK3CAMTORNPC1 | |
| SCHEMBL18766642 | 0.68 | PIK3CA (0.40) | MAP3K14PIK3CAMTORTGFBR1FLT3 | |
| SCHEMBL381224 | 0.68 | MAP3K14 (0.46) | MAP3K14PIK3CAMTORADORA2AFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119219627-A | Pyrazole derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-12-31 | — | — | CN | disclosed |