Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31320130 | 0.89 | AURKA (0.50) | AURKAPIM1CDK2GSK3BSMN1; SMN2 | |
| SCHEMBL31320129 | 0.77 | SMN1; SMN2 (0.52) | AURKAPIM1CDK2GSK3BSMN1; SMN2 | |
| SCHEMBL31320131 | 0.76 | ABL1 (0.44) | — | |
| SCHEMBL31320122 | 0.74 | TYK2 (0.43) | SMN1; SMN2MEN1KMT2AHTTTSHR | |
| SCHEMBL27791809 | 0.67 | ACP1 (0.63) | SMN1; SMN2MAPTMEN1KMT2ATP53 | |
| SCHEMBL479906 | 0.67 | ACP1 (0.63) | SMN1; SMN2MEN1KMT2AHTTTP53 | |
| SCHEMBL4600722 | 0.66 | AURKA (1.00) | AURKAPIM1CDK2GSK3BSMN1; SMN2 | |
| SCHEMBL7058895 | 0.66 | AURKA (0.61) | AURKAPIM1CDK2GSK3BSMN1; SMN2 | |
| SCHEMBL17186325 | 0.66 | KDM4E (0.60) | SMN1; SMN2MAPTMEN1KMT2ATP53 | |
| SCHEMBL3524273 | 0.65 | ACP1 (0.62) | AURKAPIM1CDK2GSK3BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024240108-A1 | ARYL UREA PARP1 INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海海和药物研究开发股份有限公司 | 2024-11-28 | — | — | WO | disclosed |