Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31320131 | 0.78 | ABL1 (0.44) | TYK2IDO1 | |
| SCHEMBL31320126 | 0.74 | AURKA (0.49) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL24857980 | 0.69 | GSK3B (0.47) | TYK2KMT2AMEN1 | |
| SCHEMBL31320125 | 0.66 | ABL1 (0.44) | TYK2 | |
| SCHEMBL31100376 | 0.65 | CRBN (0.49) | — | |
| SCHEMBL17607004 | 0.65 | HTT (0.54) | DRD2DRD4DRD3KMT2AMEN1 | |
| SCHEMBL31032862 | 0.65 | DRD2 (0.50) | DRD2DRD4DRD3KMT2AMEN1 | |
| SCHEMBL23694234 | 0.64 | MEN1 (0.38) | KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL31320119 | 0.63 | MAPK1 (0.37) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL26613698 | 0.63 | L3MBTL1 (0.42) | ALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024240108-A1 | ARYL UREA PARP1 INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海海和药物研究开发股份有限公司 | 2024-11-28 | — | — | WO | disclosed |