Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | RGS4 | P49798 | 1/20 | 0.40 |
| ▸ | RGS8 | P57771 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2672856 | 1.00 | ALDH1A1 (0.51) | ALDH1A1MAPTHSD17B10KDM4CMEN1 | |
| SCHEMBL472396 | 0.86 | ALDH1A1 (0.56) | ALDH1A1MAPTHSD17B10KDM4CMEN1 | |
| SCHEMBL17717943 | 0.85 | MAPT (0.58) | ALDH1A1MAPTHSD17B10KDM4CMEN1 | |
| SCHEMBL17717951 | 0.83 | ALDH1A1 (0.60) | ALDH1A1MAPTHSD17B10KDM4CMEN1 | |
| SCHEMBL2673155 | 0.83 | EP300 (0.51) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL2672873 | 0.80 | HSD17B2 (0.43) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2673297 | 0.78 | MAPT (0.45) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL17917603 | 0.77 | ALDH1A1 (0.59) | ALDH1A1MAPTHSD17B10KDM4CMEN1 | |
| SCHEMBL18399897 | 0.77 | GAA (0.59) | ALDH1A1MAPTHSD17B10KDM4CMEN1 | |
| SCHEMBL17358737 | 0.77 | ALDH1A1 (0.57) | ALDH1A1MAPTHSD17B10KDM4CMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778236-B1 | MODIFIED PYRIMIDINE GLUCOCORTICOID RECEPTOR MODULATORS | CORCEPT THERAPEUTICS INC (US) | 2010-07-14 | — | — | EP | disclosed |