SCHEMBL472396

SCHEMBL472396

O=C1NC(=O)N(c2ccccc2)C(=O)C1Cc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.56
MEN1 O00255 1/20 0.56
LMNA P02545 1/20 0.56
KMT2A Q03164 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
MAPT P10636 2/20 0.56
HSD17B10 Q99714 1/20 0.56
KDM4C Q9H3R0 1/20 0.56
GAA P10253 2/20 0.54
CYP1A2 P05177 2/20 0.54
CYP3A4 P08684 2/20 0.54
CYP2C19 P33261 2/20 0.54
CES2 O00748 6/20 0.49
EP300 Q09472 1/20 0.45
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17717951 0.97 ALDH1A1 (0.60) ALDH1A1MEN1LMNAKMT2ASMN1; SMN2
SCHEMBL17717943 0.92 MAPT (0.58) ALDH1A1MEN1LMNAKMT2ASMN1; SMN2
SCHEMBL17358745 0.90 ALDH1A1 (0.54) ALDH1A1MEN1LMNAKMT2ASMN1; SMN2
SCHEMBL18399897 0.90 GAA (0.59) ALDH1A1MEN1LMNAKMT2ASMN1; SMN2
SCHEMBL17917603 0.90 ALDH1A1 (0.59) ALDH1A1MEN1LMNAKMT2ASMN1; SMN2
SCHEMBL17358737 0.90 ALDH1A1 (0.57) ALDH1A1MEN1LMNAKMT2ASMN1; SMN2
SCHEMBL18334225 0.86 MAPT (0.69) ALDH1A1MEN1LMNAKMT2ASMN1; SMN2
SCHEMBL3132028 0.86 ALDH1A1 (0.51) ALDH1A1MEN1LMNAKMT2ASMN1; SMN2
SCHEMBL2672856 0.86 ALDH1A1 (0.51) ALDH1A1MEN1LMNAKMT2ASMN1; SMN2
SCHEMBL17717930 0.85 ALDH1A1 (0.53) ALDH1A1MEN1LMNAKMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250250418-A1 MIXTURE FOR INHIBITING THE EMISSION OF ALDEHYDES FROM POLYURETHANE FOAM FOR AN EXTENDED PERIOD OF TIME HUNTSMAN PETROCHEMICAL LLC 2025-08-07 US claimed
EP-4508111-A1 MIXTURE FOR INHIBITING THE EMISSION OF ALDEHYDES FROM POLYURETHANE FOAM FOR AN EXTENDED PERIOD OF TIME Huntsman Petrochemical LLC (US) 2025-02-19 EP claimed
WO-2023200641-A1 MIXTURE FOR INHIBITING THE EMISSION OF ALDEHYDES FROM POLYURETHANE FOAM FOR AN EXTENDED PERIOD OF TIME HUNTSMAN PETROCHEMICAL LLC (US) 2023-10-19 WO claimed
EP-1387659-B1 INITIATOR SYSTEM FOR ACID DENTAL FORMULATIONS 3M ESPE AG (DE) 2008-05-07 EP claimed
US-20260069510-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT COMPOSITION SHOFU INC. (JP) 2026-03-12 US disclosed
EP-3733152-B1 POWDER-LIQUID TYPE RESIN-REINFORCED DENTAL GLASS IONOMER CEMENT COMPOSITION SHOFU INC (JP) 2026-03-11 EP disclosed
EP-4659729-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT COMPOSITION Shofu Inc. (JP) 2025-12-10 EP disclosed
EP-4629958-A1 SURFACE-TREATED FILLER, DENTAL COMPOSITION CONTAINING SUCH A FILLER, PROCESS OF PRODUCTION AND USE THEREOF Solventum Intellectual Properties Company (US) 2025-10-15 EP disclosed
US-12440426-B2 Dental product with reduced extrusion forces SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2025-10-14 US disclosed
US-20250255785-A1 Dental Product with Reduced Extrusion Forces SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2025-08-14 US disclosed
US-20250250418-A1 MIXTURE FOR INHIBITING THE EMISSION OF ALDEHYDES FROM POLYURETHANE FOAM FOR AN EXTENDED PERIOD OF TIME HUNTSMAN PETROCHEMICAL LLC 2025-08-07 US disclosed
EP-4586988-A1 DENTAL PRODUCT WITH REDUCED EXTRUSION FORCES Solventum Intellectual Properties Company (US) 2025-07-23 EP disclosed
US-20110183932-A1 THREE-COMPONENT BONE CEMENT HERAEUS MEDICAL GMBH (DE) 2011-07-28 US disclosed
EP-2239275-A1 Polymerizable compositions containing salts of barbituric acid derivates 3M Innovative Properties Company (US) 2010-10-13 EP disclosed
EP-1881010-B1 Polymerizable compositions containing salts of barbituric acid derivatives 3M INNOVATIVE PROPERTIES CO (US) 2010-08-11 EP disclosed
US-20090192239-A1 POLYMERIZABLE COMPOSITIONS CONTAINING SALTS OF BARBITURIC ACID DERIVATIVES SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2009-07-30 US disclosed
EP-1881010-A1 Polymerizable compositions containing salts of barbituric acid derivatives 3M Innovative Properties Company (US) 2008-01-23 EP disclosed
WO-2007140440-A2 POLYMERIZABLE COMPOSITIONS CONTAINING SALTS OF BARBITURIC ACID DERIVATIVES 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-12-06 WO disclosed
US-6953535-B2 Initiator system for acid dental formulations 3M ESPE AG (DE) 2005-10-11 US disclosed
US-20040097613-A1 Initiator system for acid dental formulations 3M INNOVATIVE PROPERTIES COMPANY 2004-05-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260069510-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT COMPOSITION GRIN3A, HBG1, ASIC1 ALDH1A1 3441/4885MEN1 3431/4885LMNA 3276/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.