Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 18/20 | 0.88 |
| ▸ | DRD3 | P35462 | 15/20 | 0.88 |
| ▸ | DRD2 | P14416 | 14/20 | 0.88 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.88 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.88 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.88 |
| ▸ | HTR1A | P08908 | 1/20 | 0.88 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.88 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.88 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.88 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.88 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.88 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.88 |
| ▸ | HTR2A | P28223 | 1/20 | 0.88 |
| ▸ | HTR2C | P28335 | 1/20 | 0.88 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.88 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.88 |
| ▸ | HRH1 | P35367 | 1/20 | 0.88 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.88 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.88 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nemonapride SCHEMBL50209 | 0.94 | DRD4 (1.00) | DRD4DRD3DRD2NR1I2ADRB2 | |
| Nemonapride SCHEMBL50208 | 0.94 | DRD4 (1.00) | DRD4DRD3DRD2NR1I2ADRB2 | |
| Nemonapride SCHEMBL1649724 | 0.94 | DRD4 (1.00) | DRD4DRD3DRD2NR1I2ADRB2 | |
| Nemonapride SCHEMBL30442102 | 0.94 | DRD4 (1.00) | DRD4DRD3DRD2NR1I2ADRB2 | |
| Nemonapride SCHEMBL29387146 | 0.94 | DRD4 (1.00) | DRD4DRD3DRD2NR1I2ADRB2 | |
| Nemonapride SCHEMBL25247691 | 0.94 | DRD4 (1.00) | DRD4DRD3DRD2NR1I2ADRB2 | |
| Nemonapride SCHEMBL8824385 | 0.93 | DRD4 (0.98) | DRD4DRD3DRD2NR1I2ADRB2 | |
| Nemonapride SCHEMBL11462830 | 0.93 | DRD4 (0.98) | DRD4DRD3DRD2NR1I2ADRB2 | |
| Nemonapride SCHEMBL31427577 | 0.85 | DRD4 (0.78) | DRD4DRD3DRD2NR1I2ADRB2 | |
| Nemonapride SCHEMBL31544766 | 0.85 | DRD4 (0.78) | DRD4DRD3DRD2NR1I2ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260098011-A1 | DEUTERATED ORGANIC COMPOUNDS AND USES THEREOF | ENGRAIL THERAPEUTICS INC (US) | 2026-04-09 | — | — | US | disclosed |
| US-12365650-B2 | Deuterated organic compounds and uses thereof | ENGRAIL THERAPEUTICS, INC. (US) | 2025-07-22 | — | — | US | disclosed |
| US-20250011279-A1 | DEUTERATED ORGANIC COMPOUNDS AND USES THEREOF | ENGRAIL THERAPEUTICS, INC. | 2025-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12365650-B2 | Deuterated organic compounds and uses thereof | DRD2, DRD1, DRD4 | DRD4 3/4885DRD3 12/4885DRD2 1/4885 |
| US-20260098011-A1 | DEUTERATED ORGANIC COMPOUNDS AND USES THEREOF | SLC6A3, DRD2, SLC6A2 | DRD4 7/4885DRD3 9/4885DRD2 2/4885 |
| US-20250011279-A1 | DEUTERATED ORGANIC COMPOUNDS AND USES THEREOF | DRD2, DRD1, DRD4 | DRD4 3/4885DRD3 12/4885DRD2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.