SCHEMBL3132092

SCHEMBL3132092

C[C@@H](Oc1ccc(OC(F)=Cc2ccccc2)cc1)C(=O)Nc1ccccc1F

nearest known ligand 0.65

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.65
HPGD P15428 1/20 0.51
POLB P06746 2/20 0.51
TSHR P16473 3/20 0.48
TDP1 Q9NUW8 2/20 0.48
KDM4E B2RXH2 1/20 0.47
HTT P42858 1/20 0.47
ALDH1A1 P00352 2/20 0.45
MAPK1 P28482 1/20 0.45
KMT2A Q03164 4/20 0.45
MEN1 O00255 3/20 0.45
ATM Q13315 1/20 0.45
LMNA P02545 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
MAPT P10636 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3132078 1.00 GAA (0.65) GAAHPGDPOLBTSHRTDP1
SCHEMBL3137549 0.94 GAA (0.63) GAAHPGDPOLBTSHRTDP1
SCHEMBL3741645 0.94 GAA (0.63) GAAHPGDPOLBTSHRTDP1
SCHEMBL3131928 0.93 GAA (0.61) GAAHPGDPOLBTSHRTDP1
SCHEMBL3131936 0.93 GAA (0.61) GAAHPGDPOLBTSHRTDP1
SCHEMBL3734429 0.92 GAA (0.60) GAAHPGDPOLBTSHRTDP1
SCHEMBL3734431 0.92 GAA (0.60) GAAHPGDPOLBTSHRTDP1
SCHEMBL13467572 0.83 GAA (0.82) GAAHPGDPOLBTSHRTDP1
SCHEMBL28577769 0.80 GAA (0.76) GAAHPGDPOLBTSHRTDP1
SCHEMBL3134087 0.80 GAA (0.80) GAAHPGDPOLBTSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100279871-A1 OPTICALLY ACTIVE (R)-ARYLOXYPROPIONIC ACID AMIDES AND HERBICIDAL COMPOSITION COMPRISING SAME KYUNG NONG CORPORATION (KR) 2010-11-04 US claimed
EP-2183213-A2 OPTICALLY ACTIVE (R)-ARYLOXYPROPIONIC ACID AMIDES AND HERBICIDAL COMPOSITION COMPRISING SAME Kyung Nong Corporation (KR) 2010-05-12 EP claimed
WO-2009005297-A2 OPTICALLY ACTIVE (R)-ARYLOXYPROPIONIC ACID AMIDES AND HERBICIDAL COMPOSITION COMPRISING SAME KYUNG NONG CORPORATION (KR) 2009-01-08 WO claimed
US-8293774-B2 Optically active (R)-aryloxypropionic acid amides and herbicidal composition comprising same KYUNG NONG CORPORATION (KR) 2012-10-23 US disclosed
US-20100279871-A1 OPTICALLY ACTIVE (R)-ARYLOXYPROPIONIC ACID AMIDES AND HERBICIDAL COMPOSITION COMPRISING SAME KYUNG NONG CORPORATION (KR) 2010-11-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100279871-A1 OPTICALLY ACTIVE (R)-ARYLOXYPROPIONIC ACID AMIDES AND HERBICIDAL COMPOSITION COMPRISING SAME AADAC, DDT, NOTUM GAA 68/4885HPGD 1986/4885POLB 3881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.