SCHEMBL3131928

SCHEMBL3131928

Cc1ccc(/C=C(\F)Oc2ccc(O[C@H](C)C(=O)Nc3ccccc3F)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.61
POLB P06746 2/20 0.48
HPGD P15428 1/20 0.46
TSHR P16473 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
ALDH1A1 P00352 2/20 0.43
MAPK1 P28482 1/20 0.43
KDM4E B2RXH2 1/20 0.42
HTT P42858 1/20 0.42
ADORA3 P0DMS8 1/20 0.41
ADORA2A P29274 1/20 0.41
MAPT P10636 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
LMNA P02545 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
RAB9A P51151 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
ATM Q13315 1/20 0.40
TP53 P04637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3131936 1.00 GAA (0.61) GAAPOLBHPGDTSHRTDP1
SCHEMBL3741645 0.93 GAA (0.63) GAAPOLBHPGDTSHRTDP1
SCHEMBL3137549 0.93 GAA (0.63) GAAPOLBHPGDTSHRTDP1
SCHEMBL3132092 0.93 GAA (0.65) GAAPOLBHPGDTSHRTDP1
SCHEMBL3132078 0.93 GAA (0.65) GAAPOLBHPGDTSHRTDP1
SCHEMBL3734431 0.91 GAA (0.60) GAAPOLBHPGDTSHRTDP1
SCHEMBL3734429 0.91 GAA (0.60) GAAPOLBHPGDTSHRTDP1
SCHEMBL3735129 0.78 TRPM8 (0.36) GAAHPGDTSHRTDP1ALDH1A1
SCHEMBL13467572 0.78 GAA (0.82) GAAPOLBHPGDTSHRTDP1
SCHEMBL3134087 0.77 GAA (0.80) GAAPOLBHPGDTSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100279871-A1 OPTICALLY ACTIVE (R)-ARYLOXYPROPIONIC ACID AMIDES AND HERBICIDAL COMPOSITION COMPRISING SAME KYUNG NONG CORPORATION (KR) 2010-11-04 US claimed
US-8293774-B2 Optically active (R)-aryloxypropionic acid amides and herbicidal composition comprising same KYUNG NONG CORPORATION (KR) 2012-10-23 US disclosed
US-20100279871-A1 OPTICALLY ACTIVE (R)-ARYLOXYPROPIONIC ACID AMIDES AND HERBICIDAL COMPOSITION COMPRISING SAME KYUNG NONG CORPORATION (KR) 2010-11-04 US disclosed
EP-2183213-A2 OPTICALLY ACTIVE (R)-ARYLOXYPROPIONIC ACID AMIDES AND HERBICIDAL COMPOSITION COMPRISING SAME Kyung Nong Corporation (KR) 2010-05-12 EP disclosed
WO-2009005297-A2 OPTICALLY ACTIVE (R)-ARYLOXYPROPIONIC ACID AMIDES AND HERBICIDAL COMPOSITION COMPRISING SAME KYUNG NONG CORPORATION (KR) 2009-01-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100279871-A1 OPTICALLY ACTIVE (R)-ARYLOXYPROPIONIC ACID AMIDES AND HERBICIDAL COMPOSITION COMPRISING SAME AADAC, DDT, NOTUM GAA 68/4885POLB 3881/4885HPGD 1986/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.