Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.54 |
| ▸ | CTSV | O60911 | 2/20 | 0.54 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 3/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11546262 | 0.82 | PDE4A (0.49) | CYP3A4CYP2C9TSHRCYP2C19PDE4A | |
| SCHEMBL29945777 | 0.80 | IP6K1 (0.54) | CTSLCTSVNPC1RAB9AL3MBTL1 | |
| SCHEMBL23526181 | 0.80 | IP6K1 (0.54) | CTSLCTSVNPC1RAB9AL3MBTL1 | |
| SCHEMBL25548688 | 0.78 | CYP2C9 (0.70) | CYP3A4CYP2C9TSHRCYP2C19PDE4A | |
| SCHEMBL7255463 | 0.76 | CTSV (0.68) | CTSLCTSVELANESRD5A1SRD5A2 | |
| SCHEMBL1943022 | 0.76 | CTSV (0.68) | CTSLCTSVELANESRD5A1SRD5A2 | |
| SCHEMBL27041281 | 0.76 | ELANE (0.58) | CTSLCTSVKDM1AELANETSHR | |
| SCHEMBL20509552 | 0.76 | ELANE (0.58) | CTSLCTSVKDM1AELANETSHR | |
| SCHEMBL13239968 | 0.75 | CYP3A4 (0.80) | CYP3A4CYP2C9TSHRCYP2C19PDE4A | |
| SCHEMBL1013586 | 0.75 | IP6K1 (0.62) | CTSLCTSVKDM1AELANEPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250059182-A1 | SOS1 INHIBITORS | MIRATI THERAPEUTICS, INC | 2025-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250059182-A1 | SOS1 INHIBITORS | SOS1, SOS2, SOST | CTSL 3532/4885CTSV 3131/4885KDM1A 1927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.