Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.61 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.61 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.61 |
| ▸ | TTR | P02766 | 3/20 | 0.61 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.59 |
| ▸ | LTA4H | P09960 | 3/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2513436 | 0.87 | CYP1A1 (0.65) | PTGS2CYP1A1CYP1B1TTRALOX5 | |
| SCHEMBL2513437 | 0.87 | CYP1A1 (0.65) | PTGS2CYP1A1CYP1B1TTRALOX5 | |
| SCHEMBL2516448 | 0.85 | KDM4E (0.62) | PTGS2CYP1A1CYP1B1TTRALOX5 | |
| SCHEMBL2516451 | 0.85 | KDM4E (0.62) | PTGS2CYP1A1CYP1B1TTRALOX5 | |
| SCHEMBL31322129 | 0.85 | MEN1 (0.51) | PTGS2CYP1A1CYP1B1TTRALOX5 | |
| SCHEMBL5890304 | 0.84 | MEN1 (0.74) | PTGS2CYP1A1CYP1B1TTRALOX5 | |
| SCHEMBL28524463 | 0.83 | PTGS1 (0.71) | PTGS2CYP1A1CYP1B1TTRALOX5 | |
| SCHEMBL2521181 | 0.81 | CYP1A1 (0.61) | PTGS2CYP1A1CYP1B1TTRALOX5 | |
| SCHEMBL2521178 | 0.81 | CYP1A1 (0.61) | PTGS2CYP1A1CYP1B1TTRALOX5 | |
| SCHEMBL16551547 | 0.79 | MEN1 (0.82) | MEN1KMT2AKDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4483866-A1 | PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OR PREVENTION OF CANCER | Makrolife Biotech GmbH (DE) | 2025-01-01 | — | — | EP | claimed |
| EP-4483866-A1 | PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OR PREVENTION OF CANCER | Makrolife Biotech GmbH (DE) | 2025-01-01 | — | — | EP | disclosed |