SCHEMBL2521178

SCHEMBL2521178

Oc1ccc(/C=C/c2cc(Oc3ccccc3)cc(Oc3ccccc3)c2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 4/20 0.61
KDM4E B2RXH2 4/20 0.61
MEN1 O00255 4/20 0.61
MAPT P10636 4/20 0.61
KMT2A Q03164 4/20 0.61
PTGS2 P35354 4/20 0.61
TTR P02766 3/20 0.61
ALOX5 P09917 3/20 0.61
CYP1B1 Q16678 3/20 0.61
NPC1 O15118 2/20 0.61
ABL1 P00519 2/20 0.61
ABCB1 P08183 2/20 0.61
GAA P10253 2/20 0.61
BCR P11274 2/20 0.61
NQO2 P16083 2/20 0.61
PTGS1 P23219 2/20 0.61
RAB9A P51151 2/20 0.61
GFER P55789 2/20 0.61
HDAC6 Q9UBN7 2/20 0.61
MAPK1 P28482 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2521181 1.00 CYP1A1 (0.61) CYP1A1KDM4EMEN1MAPTKMT2A
SCHEMBL2513436 0.95 CYP1A1 (0.65) CYP1A1KDM4EMEN1MAPTKMT2A
SCHEMBL2513437 0.95 CYP1A1 (0.65) CYP1A1KDM4EMEN1MAPTKMT2A
SCHEMBL2516448 0.89 KDM4E (0.62) CYP1A1KDM4EMEN1MAPTKMT2A
SCHEMBL2516451 0.89 KDM4E (0.62) CYP1A1KDM4EMEN1MAPTKMT2A
SCHEMBL2516557 0.89 ESR1 (0.53) CYP1A1KDM4EMEN1MAPTKMT2A
SCHEMBL13253647 0.88 LTA4H (0.57) CYP1A1KDM4EMEN1MAPTKMT2A
SCHEMBL2516475 0.85 KDM4E (0.61) CYP1A1KDM4EMEN1MAPTKMT2A
SCHEMBL2516476 0.85 KDM4E (0.61) CYP1A1KDM4EMEN1MAPTKMT2A
SCHEMBL16280741 0.82 LTA4H (0.86) MEN1KMT2APTGS2NPC1PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9861564-B2 Valeric acid esters of resveratrol and cosmetic compositions ELC MANAGEMENT, LLC (US) 2018-01-09 US disclosed
US-9782335-B2 Malic acid esters of resveratrol and cosmetic compositions ELC MANAGEMENT LLC (US) 2017-10-10 US disclosed
US-20160303016-A1 Valeric Acid Esters Of Resveratrol And Cosmetic Compositions ELC MAN LLC (US) 2016-10-20 US disclosed
EP-2445511-B1 SKIN REPAIR COMPOSITIONS COMPRISING CIRCADIAN GENE ACTIVATORS AND A SYNERGISTIC COMBINATION OF SIRT1 GENE ACTIVATORS ELC MAN LLC (US) 2016-09-07 EP disclosed
US-20160229791-A1 Malic Acid Esters Of Resveratrol And Cosmetic Compositions ELC MAN LLC (US) 2016-08-11 US disclosed
US-9358194-B2 Succinic acid esters of resveratrol and cosmetic compositions ELC MANAGEMENT LLC (US) 2016-06-07 US disclosed
US-9295621-B2 Emulsion cosmetic compositions containing resveratrol derivatives and silicone surfactant ELC MANAGEMENT LLC (US) 2016-03-29 US disclosed
US-20160038389-A1 Succinic Acid Esters Of Resveratrol And Cosmetic Compositions ELC MAN LLC (US) 2016-02-11 US disclosed
US-9180316-B2 Butyric acid esters of resveratrol and cosmetic compositions ELC MANAGEMENT LLC (US) 2015-11-10 US disclosed
US-9162083-B2 Linoleic and Linolenic acid esters of resveratrol and cosmetic compositions ELC MANAGEMENT LLC (US) 2015-10-20 US disclosed
US-20110250251-A1 Cosmetic Methods And Compositions For Repairing Human Skin MAES DANIEL H 2011-10-13 US disclosed
US-20100216879-A1 Resveratrol Ferulate Compounds And Compositions MAES DANIEL H 2010-08-26 US disclosed
US-20100080845-A1 Cosmetic Methods And Compositions For Repairing Human Skin MAES DANIEL H 2010-04-01 US disclosed
US-20100028317-A1 Skin Repair Compositions Comprising Circadian Gene Activators And A Synergistic Combination Of Sirt1 Gene Activators ELC MANAGEMENT LLC 2010-02-04 US disclosed
US-20090047309-A1 COSMETIC METHODS AND COMPOSITIONS FOR REPAIRING HUMAN SKIN ELC MANAGEMENT LLC 2009-02-19 US disclosed
US-20090035240-A1 Aqueous Based Cosmetic Compositions Containing Resveratrol Derivatives And An Aqueous Phase Structuring Agent ELC MANAGEMENT LLC 2009-02-05 US disclosed
US-20090035243-A1 Anhydrous Cosmetic Compositions Containing Resveratrol Derivatives ELC MANAGEMENT LLC 2009-02-05 US disclosed
US-20090035242-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And Linear Or Branched Silicone ELC MANAGEMENT LLC 2009-02-05 US disclosed
US-20090035236-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And An Oil Phase Structuring Agent ELC MANAGEMENT LLC 2009-02-05 US disclosed
US-20090035237-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And Silicone Surfactant ELC MANAGEMENT LLC 2009-02-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090035243-A1 Anhydrous Cosmetic Compositions Containing Resveratrol Derivatives RB1, SIRT1, EP300 CYP1A1 1440/4885KDM4E 506/4885MEN1 3365/4885
US-20090035242-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And Linear Or Branched Silicone SQLE, SMURF1, PIK3R1 CYP1A1 2625/4885KDM4E 1188/4885MEN1 2323/4885
US-20100216879-A1 Resveratrol Ferulate Compounds And Compositions FER, FOLR1, FOLR2 CYP1A1 419/4885KDM4E 1158/4885MEN1 662/4885
US-20090047309-A1 COSMETIC METHODS AND COMPOSITIONS FOR REPAIRING HUMAN SKIN CUTA, ERCC1, OGG1 CYP1A1 253/4885KDM4E 1584/4885MEN1 2434/4885
US-20100028317-A1 Skin Repair Compositions Comprising Circadian Gene Activators And A Synergistic Combination Of Sirt1 Gene Activators CRY1, PER2, SIRT1 CYP1A1 1738/4885KDM4E 583/4885MEN1 1609/4885
US-20110250251-A1 Cosmetic Methods And Compositions For Repairing Human Skin CUTA, ERCC1, OGG1 CYP1A1 253/4885KDM4E 1584/4885MEN1 2434/4885
US-20160303016-A1 Valeric Acid Esters Of Resveratrol And Cosmetic Compositions CUTA, SUV39H1, RARA CYP1A1 348/4885KDM4E 450/4885MEN1 1277/4885
US-20090035237-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And Silicone Surfactant SMURF1, CUTA, SMURF2 CYP1A1 2419/4885KDM4E 1074/4885MEN1 2619/4885
US-20090035236-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And An Oil Phase Structuring Agent CUTA, LRAT, RARA CYP1A1 1737/4885KDM4E 1813/4885MEN1 2973/4885
US-20090035240-A1 Aqueous Based Cosmetic Compositions Containing Resveratrol Derivatives And An Aqueous Phase Structuring Agent SMARCC1, RARG, RARA CYP1A1 1950/4885KDM4E 2286/4885MEN1 1807/4885
US-20100080845-A1 Cosmetic Methods And Compositions For Repairing Human Skin CUTA, ERCC1, OGG1 CYP1A1 253/4885KDM4E 1584/4885MEN1 2434/4885
US-20160229791-A1 Malic Acid Esters Of Resveratrol And Cosmetic Compositions ME1, ME2, ME3 CYP1A1 786/4885KDM4E 421/4885MEN1 925/4885
US-20160038389-A1 Succinic Acid Esters Of Resveratrol And Cosmetic Compositions SUCNR1, SIRT1, SUCLA2 CYP1A1 1271/4885KDM4E 368/4885MEN1 2813/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.