Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | HTR6 | P50406 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | HTR2C | P28335 | 2/20 | 0.56 |
| ▸ | HTR2B | P41595 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2836378 | 0.98 | MAPT (0.67) | MAPTUSP2HTR6LMNAKDM4E | |
| SCHEMBL10445165 | 0.88 | USP2 (0.77) | MAPTUSP2LMNAALDH1A1POLB | |
| SCHEMBL18553718 | 0.86 | KDM4E (0.65) | MAPTHTR6LMNAKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL31322341 | 0.81 | HTR6 (0.66) | HTR6LMNAALDH1A1HTR2CHTR2B | |
| SCHEMBL6801727 | 0.81 | MAPT (0.65) | MAPTUSP2LMNAPOLBMEN1 | |
| SCHEMBL19392491 | 0.80 | POLB (0.80) | MAPTUSP2LMNAKDM4EALDH1A1 | |
| Aziridine SCHEMBL22778235 | 0.80 | KMT2A (0.76) | USP2LMNAKDM4EALDH1A1HTR2C | |
| SCHEMBL7131785 | 0.79 | MAPT (0.58) | MAPTUSP2LMNAKDM4EALDH1A1 | |
| SCHEMBL6802663 | 0.79 | MAPT (0.67) | MAPTUSP2LMNAALDH1A1POLB | |
| SCHEMBL30099109 | 0.78 | KMT2A (0.77) | MAPTUSP2LMNAPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119497615-A | TPK agonists and methods of using the same for treating neurodegenerative diseases | 上海日馨医药科技股份有限公司 | 2025-02-21 | — | — | CN | disclosed |