Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.44 |
| ▸ | NOS2 | P35228 | 2/20 | 0.44 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MTOR | P42345 | 3/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26643954 | 1.00 | NOS3 (0.44) | NOS3NOS2PCSK9XDHBRD4 | |
| SCHEMBL3752006 | 0.79 | MAPT (0.40) | PCSK9XDHBRD4KDM4ESMN1; SMN2 | |
| SCHEMBL30108557 | 0.79 | PCSK9 (0.41) | PCSK9XDHBRD4CHRNB2CHRNA4 | |
| SCHEMBL24774169 | 0.79 | PCSK9 (0.41) | PCSK9XDHBRD4CHRNB2CHRNA4 | |
| SCHEMBL24185394 | 0.79 | POLB (0.46) | PCSK9BRD4CHRNB2CHRNA4 | |
| SCHEMBL15723543 | 0.75 | XDH (0.45) | PCSK9XDHKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL24774174 | 0.73 | PCSK9 (0.44) | PCSK9BRD4 | |
| SCHEMBL24774165 | 0.73 | KCNJ1 (0.49) | PCSK9BRD4KDM4ENPC1RAB9A | |
| SCHEMBL24774189 | 0.73 | PCSK9 (0.44) | PCSK9BRD4 | |
| SCHEMBL30108509 | 0.73 | PCSK9 (0.44) | PCSK9BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119317626-A | Pyrrolidone derivatives as inhibitors of NF- κb-induced kinase | 詹森药业有限公司 | 2025-01-14 | — | — | CN | disclosed |