Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 2/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31323084 | 0.77 | DGAT1 (0.35) | DGAT1FPR2MAPTPOLBPYCR1 | |
| SCHEMBL26196801 | 0.72 | GAA (0.42) | FPR2MAPTPOLBNPC1RAB9A | |
| SCHEMBL3074139 | 0.70 | BRD4 (0.42) | DGAT1MAPTPOLBPYCR1SMN1; SMN2 | |
| SCHEMBL30138589 | 0.70 | BRD4 (0.42) | DGAT1MAPTPOLBPYCR1SMN1; SMN2 | |
| SCHEMBL1310479 | 0.70 | PYCR1 (0.50) | DGAT1KDM1AMAPTPOLBPYCR1 | |
| Hydrochloric Acid SCHEMBL27635784 | 0.68 | PYCR1 (0.49) | DGAT1KDM1AMAPTPOLBPYCR1 | |
| Hydrochloric Acid SCHEMBL28760014 | 0.67 | PYCR1 (0.47) | DGAT1KDM1AMAPTPOLBPYCR1 | |
| SCHEMBL23748575 | 0.67 | DGAT1 (0.38) | DGAT1FPR2KDM1AKDM1BMAPT | |
| SCHEMBL331771 | 0.66 | — | — | |
| Methoxymethane SCHEMBL27941803 | 0.65 | BRD4 (0.40) | DGAT1PYCR1SMN1; SMN2LMNAAPLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4735456-A1 | HETEROCYCLIC GLP-1 AGONISTS | Gasherbrum Bio, Inc. (US) | 2026-05-06 | — | — | EP | disclosed |
| US-20250019389-A1 | HETEROCYCLIC AGONISTS | GASHERBRUM BIO, INC. | 2025-01-16 | — | — | US | disclosed |
| WO-2025006921-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. (US) | 2025-01-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250019389-A1 | HETEROCYCLIC AGONISTS | GLP1R, GIPR, IAPP | DGAT1 499/4885FPR2 349/4885KDM1A 3192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.