Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 3/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | PITRM1 | Q5JRX3 | 2/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17964184 | 1.00 | ARG1 (0.41) | ARG1DPP4PITRM1DPP9MEN1 | |
| SCHEMBL4209356 | 0.88 | ARG1 (0.47) | ARG1DPP4PITRM1DPP9FAP | |
| SCHEMBL4209352 | 0.88 | ARG1 (0.47) | ARG1DPP4PITRM1DPP9FAP | |
| SCHEMBL9187521 | 0.82 | DPP4 (0.49) | ARG1DPP4PITRM1DPP9MEN1 | |
| Hydrochloric Acid SCHEMBL31389556 | 0.80 | DPP4 (0.48) | ARG1DPP4PITRM1DPP9MEN1 | |
| SCHEMBL27561362 | 0.76 | DPP4 (0.44) | ARG1DPP4PITRM1DPP9MEN1 | |
| SCHEMBL19815539 | 0.73 | ARG1 (0.38) | ARG1DPP4PITRM1DPP9MEN1 | |
| SCHEMBL19815535 | 0.73 | ARG1 (0.38) | ARG1DPP4PITRM1DPP9MEN1 | |
| SCHEMBL23536 | 0.72 | ARG1 (0.49) | ARG1DPP4PITRM1DPP9MEN1 | |
| SCHEMBL23535 | 0.72 | ARG1 (0.49) | ARG1DPP4PITRM1DPP9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4735438-A2 | HETEROBIFUNCTIONAL COMPOUNDS FOR THE DEGRADATION OF KRAS | Merck Patent GmbH (DE) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025006783-A2 | HETEROBIFUNCTIONAL COMPOUNDS FOR THE DEGRADATION OF KRAS | MERCK PATENT GMBH (DE) | 2025-01-02 | — | — | WO | disclosed |