Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | AGPAT2 | O15120 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL311616 | 0.93 | KDM4E (0.52) | MAOBAGPAT2HPGDKDM4EHSD17B10 | |
| SCHEMBL312986 | 0.92 | MAOB (0.47) | MAOBAGPAT2HPGDKDM4EHSD17B10 | |
| SCHEMBL313410 | 0.85 | MAOB (0.48) | MAOBAGPAT2HPGDKDM4EHSD17B10 | |
| SCHEMBL312286 | 0.84 | MAOB (0.44) | MAOBAGPAT2HPGDKDM4EHSD17B10 | |
| SCHEMBL311430 | 0.81 | KDM4E (0.53) | MAOBAGPAT2HPGDKDM4EHSD17B10 | |
| SCHEMBL311791 | 0.81 | HPGD (0.51) | MAOBHPGDKDM4EHSD17B10LMNA | |
| SCHEMBL312367 | 0.78 | KDM4E (0.52) | MAOBHPGDKDM4EHSD17B10LMNA | |
| SCHEMBL324201 | 0.77 | HPGD (0.61) | MAOBHPGDKDM4EHSD17B10LMNA | |
| SCHEMBL312716 | 0.74 | MAOB (0.43) | MAOBAGPAT2HPGDKDM4EHSD17B10 | |
| SCHEMBL312223 | 0.74 | AKR1B1 (0.56) | MAOBHPGDKDM4EHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093273-B2 | Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2012-01-10 | — | — | US | disclosed |
| EP-2332527-A2 | Flavanoids and Isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2011-06-15 | — | — | EP | disclosed |