Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | AGPAT2 | O15120 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL311616 | 0.87 | KDM4E (0.52) | MAOBAGPAT2MAPTRAB9AHPGD | |
| SCHEMBL312286 | 0.86 | MAOB (0.44) | MAOBAGPAT2NPC1HPGDKDM4E | |
| SCHEMBL312986 | 0.85 | MAOB (0.47) | MAOBAGPAT2NPC1RAB9AHPGD | |
| SCHEMBL313237 | 0.85 | MAOB (0.47) | MAOBAGPAT2NPC1RAB9AHPGD | |
| SCHEMBL313004 | 0.82 | ATM (0.52) | MAOBMAPTHPGDKDM4EHSD17B10 | |
| SCHEMBL311430 | 0.77 | KDM4E (0.53) | MAOBAGPAT2NPC1MAPTRAB9A | |
| SCHEMBL312367 | 0.74 | KDM4E (0.52) | MAOBNPC1MAPTRAB9AHPGD | |
| SCHEMBL311753 | 0.73 | ALDH1A1 (0.43) | MAOBMAPTHPGDKDM4EHSD17B10 | |
| SCHEMBL311431 | 0.73 | HPGD (0.46) | MAOBNPC1MAPTHPGDKDM4E | |
| SCHEMBL313540 | 0.73 | MAPT (0.41) | MAOBMAPTHPGDKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093273-B2 | Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2012-01-10 | — | — | US | disclosed |
| EP-2332527-A2 | Flavanoids and Isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2011-06-15 | — | — | EP | disclosed |