Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL311616 | 0.93 | KDM4E (0.52) | MAOBHPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL313237 | 0.92 | MAOB (0.47) | MAOBHPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL313410 | 0.85 | MAOB (0.48) | MAOBHPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL312286 | 0.84 | MAOB (0.44) | MAOBHPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL311430 | 0.81 | KDM4E (0.53) | MAOBHPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL312223 | 0.81 | AKR1B1 (0.56) | MAOBAKR1B1HPGDKDM4EALDH1A1 | |
| SCHEMBL312367 | 0.78 | KDM4E (0.52) | MAOBHPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL324201 | 0.74 | HPGD (0.61) | MAOBAKR1B1HPGDKDM4EALDH1A1 | |
| SCHEMBL311784 | 0.74 | AKR1B1 (0.46) | MAOBAKR1B1HPGDKDM4EALDH1A1 | |
| SCHEMBL311390 | 0.74 | AKR1B1 (0.41) | MAOBAKR1B1HPGDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1838296-B1 | FLAVANOIDS AND ISOFLAVANOIDS FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASES | RESVERLOGIX CORP (CA) | 2012-08-08 | — | — | EP | disclosed |
| US-8093273-B2 | Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2012-01-10 | — | — | US | disclosed |
| EP-2332527-A2 | Flavanoids and Isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2011-06-15 | — | — | EP | disclosed |