Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.55 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31453263 | 0.83 | GAA (0.45) | KDM4EGAAMEN1KMT2ATSHR | |
| SCHEMBL18711481 | 0.82 | USP2 (0.53) | BPTFNOTUMCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL18701824 | 0.78 | BPTF (0.46) | BPTFNOTUMMEN1KMT2ASIGMAR1 | |
| SCHEMBL14704613 | 0.78 | BPTF (0.53) | BPTFNOTUMCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL3867043 | 0.76 | HTR1A (0.67) | ALDH1A1MEN1KMT2AUSP2TSHR | |
| SCHEMBL2297674 | 0.76 | NOTUM (0.58) | BPTFNOTUMALDH1A1KDM4EMEN1 | |
| SCHEMBL15596306 | 0.74 | GPR119 (0.67) | GPR119 | |
| SCHEMBL10111733 | 0.74 | GPR119 (0.67) | GPR119 | |
| SCHEMBL15515714 | 0.74 | BPTF (0.63) | BPTFNOTUMCHRNB2CHRNA3CHRNA7 | |
| SCHEMBL14060380 | 0.74 | GFER (0.47) | BPTFNOTUMALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4512807-A1 | BICYCLOAMINE CARBOXAMIDE DERIVATIVE | Sumitomo Pharma Co., Ltd. (JP) | 2025-02-26 | — | — | EP | claimed |
| CN-119053606-A | Bicyclic carboxamide derivatives | 住友制药株式会社 | 2024-11-29 | — | — | CN | claimed |
| CN-119053606-A | Bicyclic carboxamide derivatives | 住友制药株式会社 | 2024-11-29 | — | — | CN | disclosed |