SCHEMBL31324174

SCHEMBL31324174

COC(=O)Cc1cccc(Nc2ccc(Cl)cc2)c1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ SLC7A5 Q01650 1/20 0.50
▸ MAPT P10636 4/20 0.49
▸ ALDH1A1 P00352 2/20 0.49
▸ P2RX3 P56373 2/20 0.48
▸ L3MBTL1 Q9Y468 1/20 0.47
▸ CNR1 P21554 2/20 0.45
▸ SYK P43405 1/20 0.45
▸ KMT2A Q03164 3/20 0.44
▸ MEN1 O00255 2/20 0.44
▸ POLB P06746 2/20 0.44
▸ NPC1 O15118 1/20 0.44
▸ RAB9A P51151 1/20 0.44
▸ SIRT2 Q8IXJ6 1/20 0.43
▸ KLK7 P49862 1/20 0.43
▸ MTNR1A P48039 2/20 0.43
▸ MTNR1B P49286 2/20 0.43
▸ LMNA P02545 1/20 0.43
▸ MAPK1 P28482 1/20 0.43
▸ ATM Q13315 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7338826 0.88 SLC7A5 (0.58) SLC7A5MAPTALDH1A1SYKKMT2A
SCHEMBL31324192 0.86 MAPT (0.50) MAPTALDH1A1L3MBTL1CNR1KMT2A
SCHEMBL31324190 0.85 MAPT (0.63) MAPTALDH1A1CNR1KMT2AMEN1
SCHEMBL378633 0.80 SLC7A5 (0.55) SLC7A5ALDH1A1KMT2AMEN1
SCHEMBL693860 0.79 SLC7A5 (0.54) SLC7A5MAPTALDH1A1SYKKMT2A
SCHEMBL12400239 0.78 SLC7A5 (0.68) SLC7A5MAPTALDH1A1NPC1RAB9A
Methylamine SCHEMBL15743165 0.77 SLC7A5 (0.56) SLC7A5ALDH1A1KMT2AMEN1
SCHEMBL17869670 0.77 SLC7A5 (0.56) SLC7A5MAPTALDH1A1SYKKMT2A
SCHEMBL11445117 0.77 HPGD (0.47) SLC7A5MAPTALDH1A1L3MBTL1KMT2A
SCHEMBL12440458 0.77 P2RX3 (0.58) SLC7A5ALDH1A1P2RX3L3MBTL1CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4743082-A1 CARBAZOLE COMPOUNDS AND THEIR USE IN THERAPY, IN THE TREATMENT OF A RESPIRATORY INFECTION UCL Business Ltd (GB) 2026-05-20 — — EP disclosed
WO-2025012634-A1 CARBAZOLE COMPOUNDS AND THEIR USE IN THERAPY, IN THE TREATMENT OF A RESPIRATORY INFECTION UCL BUSINESS LTD (GB) 2025-01-16 — — WO disclosed
Send feedback