Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MPL | P40238 | 2/20 | 0.53 |
| ▸ | KIF11 | P52732 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RGS12 | O14924 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31324205 | 0.84 | KDM4E (0.81) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL1648901 | 0.82 | KDM4E (0.74) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL31716571 | 0.81 | KDM4E (0.60) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| Methane SCHEMBL8206725 | 0.81 | KDM4E (0.72) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL24440010 | 0.79 | KDM4E (0.68) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL6009663 | 0.78 | KIF11 (0.68) | KDM4EMAPTALDH1A1HSD17B10KIF11 | |
| Carbazole SCHEMBL30528404 | 0.77 | KDM4E (0.58) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL6288056 | 0.77 | KDM4E (0.77) | KDM4EMAPTALDH1A1HSD17B10MEN1 | |
| SCHEMBL31324164 | 0.77 | MEN1 (0.69) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| Carbazole SCHEMBL30528377 | 0.77 | KDM4E (0.55) | KDM4EMAPTALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022103149-A1 | NOVEL CARBAZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF CANCER COMPRISING SAME AS ACTIVE INGREDIENT | 주식회사 큐라클 | 2022-05-19 | — | — | WO | disclosed |