Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.33 |
| ▸ | TUBB | P07437 | 2/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.33 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.33 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.33 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3128389 | 0.76 | CYP3A4 (0.53) | CYP3A4ALOX15HSD17B10BRD4NEK1 | |
| SCHEMBL3134110 | 0.76 | ALOX15 (0.53) | CYP3A4ALOX15HSD17B10BRD4NEK1 | |
| SCHEMBL3138775 | 0.73 | CYP3A4 (0.50) | CYP3A4ALOX15HSD17B10BRD4NEK1 | |
| SCHEMBL7459304 | 0.72 | ALOX15 (0.53) | CYP3A4ALOX15HSD17B10BRD4MAPT | |
| SCHEMBL3137327 | 0.72 | CYP3A4 (0.48) | CYP3A4ALOX15HSD17B10BRD4MAPT | |
| SCHEMBL3132405 | 0.72 | HSD17B10 (0.48) | CYP3A4ALOX15HSD17B10BRD4NEK1 | |
| SCHEMBL3137553 | 0.72 | ALOX15 (0.48) | CYP3A4ALOX15HSD17B10BRD4NEK1 | |
| SCHEMBL23137330 | 0.71 | ALOX15 (0.76) | CYP3A4ALOX15HSD17B10BRD4MAPT | |
| SCHEMBL5844871 | 0.71 | BACE1 (0.52) | CYP3A4ALOX15HSD17B10ALOX5APFEN1 | |
| SCHEMBL7463846 | 0.71 | CYP3A4 (0.52) | CYP3A4ALOX15HSD17B10BRD4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080235882-A1 | Novel O-Aminophenol Derivatives and Colorants Containing Said Compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2008-10-02 | — | — | US | claimed |
| CN-1997637-A | Novel o-aminophenol derivatives and colorants containing said compounds | WELLA AG (DE) | 2007-07-11 | — | — | CN | claimed |
| EP-1768971-A1 | NOVEL O-AMINOPHENOL DERIVATIVES AND COLORANTS CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2007-04-04 | — | — | EP | claimed |
| WO-2006007896-A1 | NOVEL O-AMINOPHENOL DERIVATIVES AND COLORANTS CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2006-01-26 | — | — | WO | claimed |
| US-7641702-B2 | O-Aminophenol derivatives and colorants containing said compounds | WELLA AG (DE) | 2010-01-05 | — | — | US | disclosed |
| US-20080235882-A1 | Novel O-Aminophenol Derivatives and Colorants Containing Said Compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2008-10-02 | — | — | US | disclosed |
| CN-1997637-A | Novel o-aminophenol derivatives and colorants containing said compounds | WELLA AG (DE) | 2007-07-11 | — | — | CN | disclosed |
| EP-1768971-A1 | NOVEL O-AMINOPHENOL DERIVATIVES AND COLORANTS CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2007-04-04 | — | — | EP | disclosed |
| WO-2006007896-A1 | NOVEL O-AMINOPHENOL DERIVATIVES AND COLORANTS CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2006-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080235882-A1 | Novel O-Aminophenol Derivatives and Colorants Containing Said Compounds | CBR3, KRT18, F12 | CYP3A4 526/4885ALOX15 3757/4885HSD17B10 2013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.