SCHEMBL31324865

SCHEMBL31324865

Cc1ccc(S(=O)(=O)n2ccc3c(B4OC(C)(C)C(C)(C)O4)ccnc32)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.50
ELANE P08246 1/20 0.37
PRTN3 P24158 1/20 0.37
PKM P14618 2/20 0.37
CYP2C19 P33261 2/20 0.36
POLB P06746 1/20 0.36
ALDH3A1 P30838 1/20 0.36
HTT P42858 1/20 0.36
NOD1 Q9Y239 1/20 0.36
RAPGEF4 Q8WZA2 2/20 0.36
HTR6 P50406 2/20 0.35
CYP19A1 P11511 1/20 0.35
BRD4 O60885 1/20 0.35
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
PTGDR2 Q9Y5Y4 1/20 0.34
GAA P10253 1/20 0.33
MET P08581 1/20 0.33
TSHR P16473 1/20 0.33
HDAC3 O15379 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1394996 1.00 L3MBTL1 (0.50) L3MBTL1ELANEPRTN3PKMCYP2C19
SCHEMBL1394497 0.90 CYP2C19 (0.48) L3MBTL1PKMCYP2C19HTTHTR6
SCHEMBL14510682 0.85 L3MBTL1 (0.45) L3MBTL1ELANEPRTN3PKMCYP2C19
SCHEMBL29604912 0.83 L3MBTL1 (0.49) L3MBTL1PKMCYP2C19POLBALDH3A1
SCHEMBL1891374 0.83 L3MBTL1 (0.49) L3MBTL1PKMCYP2C19POLBALDH3A1
SCHEMBL26720584 0.83 L3MBTL1 (0.44) L3MBTL1ELANEPRTN3PKMCYP2C19
SCHEMBL15649352 0.83 HTR6 (0.34) HTR6CA1CA2
SCHEMBL16908341 0.82 PTGDR2 (0.40) L3MBTL1ELANEPRTN3PKMCYP2C19
SCHEMBL16516509 0.81 L3MBTL1 (0.47) L3MBTL1PKMCYP2C19POLBALDH3A1
SCHEMBL21354067 0.80 L3MBTL1 (0.41) L3MBTL1ELANEPRTN3PKMRAPGEF4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735114-A1 SUBSTITUTED THIENO [3,2-B]PYRIDINES AS INHIBITORS OF PROTEIN KINASES Masarykova Univerzita (CZ) 2026-05-06 EP disclosed
WO-2025002491-A1 SUBSTITUTED THIENO [3,2-B]PYRIDINES AS INHIBITORS OF PROTEIN KINASES MASARYKOVA UNIVERZITA (CZ) 2025-01-02 WO disclosed