Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD known ✓ | O00329 | 1/20 | 0.30 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL30165901 | 0.98 | TMPRSS2 (0.39) | TMPRSS2 | |
| Sulfuric Acid SCHEMBL30165951 | 0.98 | TMPRSS2 (0.39) | TMPRSS2 | |
| SCHEMBL30165917 | 0.96 | TMPRSS2 (0.40) | TMPRSS2PIK3CD | |
| Bromide SCHEMBL30165903 | 0.95 | TMPRSS2 (0.40) | TMPRSS2PIK3CD | |
| SCHEMBL30516180 | 0.95 | TMPRSS2 (0.41) | TMPRSS2PIK3CD | |
| Phosphoric Acid SCHEMBL30165932 | 0.93 | TMPRSS2 (0.40) | TMPRSS2 | |
| Maleic Acid SCHEMBL30165883 | 0.92 | TMPRSS2 (0.38) | TMPRSS2 | |
| SCHEMBL31239307 | 0.85 | TMPRSS2 (0.39) | TMPRSS2 | |
| SCHEMBL31239302 | 0.85 | TMPRSS2 (0.39) | TMPRSS2 | |
| SCHEMBL31239301 | 0.85 | TMPRSS2 (0.39) | TMPRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115572298-B | Crystal form, preparation method and application of nucleoside analogue and salt thereof | 苏州旺山旺水生物医药股份有限公司 | 2024-11-08 | — | — | CN | disclosed |