Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | CASP1 | P29466 | 3/20 | 0.37 |
| ▸ | CASP7 | P55210 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31326705 | 0.82 | KDM4E (0.37) | KDM4EALDH1A1HPGDTSHRTP53 | |
| SCHEMBL31326712 | 0.81 | KMT2A (0.49) | KDM4EALDH1A1HPGDTSHRTP53 | |
| SCHEMBL31326704 | 0.73 | ALDH1A1 (0.42) | KDM4EALDH1A1HPGDTSHRTP53 | |
| SCHEMBL31326609 | 0.71 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDTSHRTP53 | |
| SCHEMBL31326690 | 0.70 | MTOR (0.44) | LRRK2CHEK1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL9334039 | 0.69 | NQO2 (0.57) | KDM4EALDH1A1HPGDTSHRTP53 | |
| SCHEMBL31326702 | 0.68 | ALDH1A1 (0.39) | KDM4EALDH1A1HPGDTSHRTP53 | |
| SCHEMBL24312598 | 0.68 | NPC1 (0.42) | LRRK2KDM4EALDH1A1TP53MAPT | |
| SCHEMBL24454253 | 0.67 | GRIN2D (0.43) | LRRK2 | |
| SCHEMBL31184383 | 0.65 | POLB (0.70) | KDM4EALDH1A1HPGDTSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709714-A1 | SUBSTITUTED QUINOXALINES | Mirati Therapeutics, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024238221-A1 | SUBSTITUTED QUINOXALINES | Mirati Therapeutics, Inc. (US) | 2024-11-21 | — | — | WO | disclosed |