Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KHK | P50053 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | CASP7 | P55210 | 2/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CLK1 | P49759 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31326609 | 0.90 | ALDH1A1 (0.46) | KMT2APOLBMAPK1ALDH1A1HPGD | |
| SCHEMBL31184383 | 0.83 | POLB (0.70) | KMT2APOLBALDH1A1HPGDMAPT | |
| SCHEMBL31326690 | 0.81 | MTOR (0.44) | ALDH1A1KDM4E | |
| SCHEMBL31326660 | 0.81 | LRRK2 (0.43) | KMT2APOLBALDH1A1HPGDMEN1 | |
| SCHEMBL31326705 | 0.80 | KDM4E (0.37) | KMT2APOLBMAPK1ALDH1A1HPGD | |
| SCHEMBL31326704 | 0.78 | ALDH1A1 (0.42) | KMT2APOLBALDH1A1HPGDMEN1 | |
| SCHEMBL30762357 | 0.77 | ALDH1A1 (0.52) | KMT2APOLBMAPK1ALDH1A1HPGD | |
| SCHEMBL2347506 | 0.76 | CTSK (0.54) | POLBMAPK1ALDH1A1HPGDKHK | |
| SCHEMBL9334039 | 0.76 | NQO2 (0.57) | KMT2APOLBALDH1A1HPGDMEN1 | |
| SCHEMBL31326702 | 0.76 | ALDH1A1 (0.39) | KMT2APOLBMAPK1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709714-A1 | SUBSTITUTED QUINOXALINES | Mirati Therapeutics, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024238221-A1 | SUBSTITUTED QUINOXALINES | Mirati Therapeutics, Inc. (US) | 2024-11-21 | — | — | WO | disclosed |