Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TRPV6 | Q9H1D0 | 2/20 | 0.31 |
| ▸ | PRCP | P42785 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL31327095 | 0.87 | KDM4E (0.37) | KDM4EALDH1A1ALOX15SIGMAR1MEN1 | |
| Trifluoroacetic Acid SCHEMBL17025592 | 0.84 | KDM1A (0.39) | KDM1APRCPHRH3HPGDSDPP4 | |
| Trifluoroacetic Acid SCHEMBL31327132 | 0.83 | DPP7 (0.35) | KDM4EALDH1A1ALOX15SIGMAR1MEN1 | |
| Trifluoroacetic Acid SCHEMBL1700238 | 0.79 | HRH3 (0.43) | HRH3 | |
| Trifluoroacetic Acid SCHEMBL31327064 | 0.78 | KDM4E (0.35) | KDM4EALDH1A1ALOX15SIGMAR1HRH3 | |
| Trifluoroacetic Acid SCHEMBL31327037 | 0.78 | IRAK4 (0.36) | KDM4EALDH1A1ALOX15TDP1MEN1 | |
| Trifluoroacetic Acid SCHEMBL1700180 | 0.77 | L3MBTL1 (0.39) | KDM4EALDH1A1PRCPHRH3DPP4 | |
| Trifluoroacetic Acid SCHEMBL21645222 | 0.77 | L3MBTL1 (0.39) | KDM4EALDH1A1PRCPHRH3DPP4 | |
| Trifluoroacetic Acid SCHEMBL31327141 | 0.77 | HRH3 (0.40) | SIGMAR1HRH3DPP4DPP8DPP7 | |
| Trifluoroacetic Acid SCHEMBL31327131 | 0.75 | MEN1 (0.34) | KDM4EALDH1A1ALOX15MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250066383-A1 | PDE 7 MODULATOR COMPOUNDS | OMEROS CORPORATION | 2025-02-27 | — | — | US | disclosed |
| WO-2025042956-A1 | PDE 7 MODULATOR COMPOUNDS | OMEROS CORPORATION (US) | 2025-02-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250066383-A1 | PDE 7 MODULATOR COMPOUNDS | PDE7A, PDE3A, PDE3B | KDM4E 915/4885ALDH1A1 1479/4885KDM1A 847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.