SCHEMBL31327372

SCHEMBL31327372

O=C(O)c1cccc(C(=O)ON2C(=O)CCC2=O)c1-c1c2ccc(=O)cc-2oc2cc(O)ccc12.O=C(ON1C(=O)CCC1=O)c1ccc(C(=O)O)c(-c2c3ccc(=O)cc-3oc3cc(O)ccc23)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ USP2 O75604 3/20 0.50
▸ L3MBTL1 Q9Y468 1/20 0.50
▸ DNASE1L3 Q13609 1/20 0.48
▸ PRMT1 Q99873 1/20 0.48
▸ MEN1 O00255 2/20 0.47
▸ POLB P06746 2/20 0.47
▸ KMT2A Q03164 2/20 0.47
▸ ALPL P05186 1/20 0.47
▸ ALPI P09923 1/20 0.47
▸ ALPG P10696 1/20 0.47
▸ ATM Q13315 1/20 0.46
▸ PLEC Q15149 1/20 0.46
▸ CA9 Q16790 8/20 0.44
▸ CA1 P00915 7/20 0.43
▸ CA2 P00918 7/20 0.43
▸ ESR1 P03372 1/20 0.42
▸ ALB P02768 1/20 0.42
▸ CA12 O43570 3/20 0.42
▸ CA14 Q9ULX7 2/20 0.39
▸ CDC25A P30304 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29415506 0.94 USP2 (0.56) USP2L3MBTL1DNASE1L3PRMT1MEN1
SCHEMBL2054802 0.94 USP2 (0.56) USP2L3MBTL1DNASE1L3PRMT1MEN1
SCHEMBL29399313 0.91 USP2 (0.58) USP2L3MBTL1DNASE1L3PRMT1MEN1
SCHEMBL30179280 0.88 USP2 (0.62) USP2L3MBTL1DNASE1L3PRMT1MEN1
SCHEMBL799734 0.88 USP2 (0.62) USP2L3MBTL1DNASE1L3PRMT1MEN1
SCHEMBL3728723 0.84 USP2 (0.57) USP2L3MBTL1DNASE1L3PRMT1MEN1
SCHEMBL6693395 0.83 USP2 (0.56) USP2L3MBTL1DNASE1L3PRMT1MEN1
SCHEMBL29352834 0.83 USP2 (0.56) USP2L3MBTL1DNASE1L3PRMT1MEN1
SCHEMBL10226304 0.82 MEN1 (0.60) USP2L3MBTL1DNASE1L3PRMT1MEN1
SCHEMBL15150533 0.81 USP2 (0.60) USP2L3MBTL1DNASE1L3PRMT1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240425924-A1 KIT FOR EVALUATING THROMBOMODULIN MRNA IN MATERNAL BLOOD FOR THE EARLY PREDICTION OF PRE-ECLAMPSIA PONTIFICIA UNIVERSIDAD JAVERIANA (CO) 2024-12-26 — — US disclosed
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