Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | PTPRF | P10586 | 1/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31340004 | 0.82 | PIN1 (0.46) | POLBSMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL31327417 | 0.81 | PTGS2 (0.48) | PTGS2ATMHPGDRAB9ANPSR1 | |
| SCHEMBL7853227 | 0.74 | SMN1; SMN2 (0.63) | POLBSMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL21121210 | 0.72 | MAPT (0.59) | SMN1; SMN2KMT2AMEN1MAPTCYP2C19 | |
| SCHEMBL21163901 | 0.72 | KMT2A (0.48) | SMN1; SMN2KMT2AMEN1MAPTCYP2C19 | |
| SCHEMBL5416820 | 0.71 | AURKA (0.54) | ATMRAB9AMAPK1NPSR1 | |
| SCHEMBL4820842 | 0.71 | MEN1 (0.65) | POLBSMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL31339996 | 0.70 | CLK1 (0.47) | MAPT | |
| SCHEMBL3158234 | 0.70 | PTPRF (0.87) | POLBSMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL5649144 | 0.70 | SMN1; SMN2 (1.00) | POLBSMN1; SMN2KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118994031-A | Novel pyrimidine biphenyl derivative with anti-tumor activity and preparation method and application thereof | 吉林大学 | 2024-11-22 | — | — | CN | disclosed |