SCHEMBL31327481

SCHEMBL31327481

C#CCN(CC#C)c1ccc(C)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
CA4 P22748 1/20 0.53
CA7 P43166 1/20 0.53
CA9 Q16790 1/20 0.53
PYCR1 P32322 3/20 0.52
CYP2C19 P33261 1/20 0.45
IGLV6-57 P01721 2/20 0.45
TSHR P16473 2/20 0.42
ALDH1A1 P00352 2/20 0.42
TYMS P04818 2/20 0.40
DHFR P00374 1/20 0.40
ACHE P22303 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
LMNA P02545 2/20 0.35
USP2 O75604 1/20 0.35
CYP3A4 P08684 1/20 0.35
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13338103 0.88 CA12 (0.63) CA12CA1CA2CA4CA7
SCHEMBL27371476 0.79 CYP2C19 (0.53) PYCR1CYP2C19TSHRTYMSDHFR
SCHEMBL27265464 0.79 PYCR1 (0.57) CA12CA1CA2CA4CA7
SCHEMBL21755799 0.78 CA12 (0.50) CA12CA1CA2CA4CA7
SCHEMBL14947360 0.77 GLA (0.48) PYCR1CYP2C19TSHRALDH1A1ACHE
SCHEMBL121718 0.77 CA12 (0.53) CA12CA1CA2CA4CA7
SCHEMBL17076687 0.77 CA12 (0.58) CA12CA1CA2CA4CA7
SCHEMBL10126415 0.77 CA12 (0.53) CA12CA1CA2CA4CA7
SCHEMBL10430153 0.76 CA12 (0.52) CA12CA1CA2CA4CA7
SCHEMBL23960143 0.74 CA12 (0.50) CA12CA1CA2CA4CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118993898-A 1, 7-Dihalogenated-1, 6-heptadiyne derivative and preparation method thereof, and polymer of 1, 7-dihalogenated-1, 6-heptadiyne derivative and preparation method and application thereof 西南林业大学 2024-11-22 CN disclosed