Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 15/20 | 0.64 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.61 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31328299 | 0.86 | SIRT1 (0.65) | SIRT1SIRT2SIRT3ALOX15SMN1; SMN2 | |
| SCHEMBL31328310 | 0.82 | MAPT (0.66) | SIRT1SIRT2SIRT3ALOX15SMN1; SMN2 | |
| SCHEMBL31328301 | 0.82 | MAPT (0.66) | SIRT1SIRT2SIRT3ALOX15SMN1; SMN2 | |
| SCHEMBL3484154 | 0.78 | SIRT1 (1.00) | SIRT1SIRT2SIRT3ALOX15SMN1; SMN2 | |
| SCHEMBL1275557 | 0.76 | SIRT1 (1.00) | SIRT1SIRT2SIRT3ALOX15SMN1; SMN2 | |
| SCHEMBL1874310 | 0.76 | SIRT1 (1.00) | SIRT1SIRT2SIRT3ALOX15SMN1; SMN2 | |
| SCHEMBL1870769 | 0.76 | SIRT1 (1.00) | SIRT1SIRT2SIRT3ALOX15SMN1; SMN2 | |
| SCHEMBL8251110 | 0.75 | SIRT1 (1.00) | SIRT1SIRT2SIRT3ALOX15SMN1; SMN2 | |
| SCHEMBL1873844 | 0.75 | SIRT1 (1.00) | SIRT1SIRT2SIRT3ALOX15SMN1; SMN2 | |
| SCHEMBL13960995 | 0.75 | SIRT1 (0.83) | SIRT1SIRT2SIRT3ALOX15SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4729510-A1 | INDOLE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Suzhou Merna Therapeutics Co. Ltd (CN) | 2026-04-22 | — | — | EP | disclosed |
| WO-2025007928-A1 | INDOLE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州湃芮生物科技有限公司 | 2025-01-09 | — | — | WO | disclosed |