Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 13/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.41 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4780145 | 1.00 | MEN1 (0.64) | MEN1KMT2AMAPTLMNAGAA | |
| SCHEMBL4729264 | 0.90 | MEN1 (0.68) | MEN1KMT2AMAPTLMNAGAA | |
| SCHEMBL8220387 | 0.87 | MEN1 (0.67) | MEN1KMT2AMAPTLMNAGAA | |
| SCHEMBL34464423 | 0.84 | MEN1 (0.60) | MEN1KMT2AMAPTLMNAGAA | |
| SCHEMBL31328320 | 0.84 | MEN1 (0.60) | MEN1KMT2AMAPTLMNAGAA | |
| SCHEMBL4727202 | 0.83 | SIRT1 (0.53) | MEN1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL8221598 | 0.82 | SIRT1 (0.60) | MEN1KMT2ALMNAALOX15TP53 | |
| SCHEMBL4727105 | 0.82 | SIRT1 (0.60) | MEN1KMT2ALMNAALOX15TP53 | |
| SCHEMBL8223572 | 0.82 | SIRT1 (0.60) | MEN1KMT2ALMNAALOX15TP53 | |
| SCHEMBL16266056 | 0.81 | MEN1 (0.67) | MEN1KMT2AMAPTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025007928-A1 | INDOLE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州湃芮生物科技有限公司 | 2025-01-09 | — | — | WO | disclosed |