⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2692984 | 0.77 | KDM4E (0.31) | — | |
| SCHEMBL2036437 | 0.77 | KDM4E (0.33) | — | |
| SCHEMBL1057403 | 0.74 | L3MBTL1 (0.32) | — | |
| SCHEMBL11481715 | 0.74 | — | — | |
| SCHEMBL83504 | 0.72 | TSHR (0.33) | — | |
| SCHEMBL506194 | 0.72 | ACHE (0.41) | — | |
| SCHEMBL1058536 | 0.72 | KDM4E (0.31) | — | |
| SCHEMBL3129262 | 0.72 | ACHE (0.37) | — | |
| SCHEMBL10453570 | 0.69 | CYP1A2 (0.32) | — | |
| SCHEMBL9538530 | 0.69 | EPHX1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116516696-B | Preparation and application of polyurethane-acrylic ester fluorine-free water repellent agent disperse dye integrated product | 青岛大学 | 2025-05-06 | — | — | CN | claimed |
| CN-119841720-A | Method for preparing tetramethyl cyclobutanedione | 中国石油化工股份有限公司 | 2025-04-18 | — | — | CN | claimed |
| EP-4255873-A1 | PRODUCTION OF 2,2,4,4-TETRAMETHYLCYCLOBUTANE-1, 3-DIOL FROM ISOBUTANOL USING A HOMOGENEOUS CATALYST | Eastman Chemical Company (US) | 2023-10-11 | — | — | EP | claimed |
| EP-4255881-A1 | PRODUCTION OF 2,2,4, 4-TETRAMETHYLCYCLOBUTANE-1, 3-DIOL FROM SECONDARY ALCOHOLS AND 2,2,4,4-TETRAMETHYLCYCLOBUTANEDIONE USING HOMOGENEOUS CATALYSTS | Eastman Chemical Company (US) | 2023-10-11 | — | — | EP | claimed |
| CN-116516696-A | Preparation and application of polyurethane-acrylic ester fluorine-free water repellent agent disperse dye integrated product | 青岛大学 | 2023-08-01 | — | — | CN | claimed |
| WO-2022119792-A1 | PRODUCTION OF 2,2,4,4-TETRAMETHYLCYCLOBUTANE-1, 3-DIOL FROM ISOBUTANOL USING A HOMOGENEOUS CATALYST | EASTMAN CHEMICAL COMPANY (US) | 2022-06-09 | — | — | WO | claimed |
| WO-2022119793-A1 | PRODUCTION OF 2,2,4, 4-TETRAMETHYLCYCLOBUTANE-1, 3-DIOL FROM SECONDARY ALCOHOLS AND 2,2,4,4-TETRAMETHYLCYCLOBUTANEDIONE USING HOMOGENEOUS CATALYSTS | EASTMAN CHEMICAL COMPANY (US) | 2022-06-09 | — | — | WO | claimed |
| CN-119841720-B | Method for preparing tetramethyl cyclobutanedione | 中国石油化工股份有限公司 | 2026-01-06 | — | — | CN | disclosed |
| CN-116516696-B | Preparation and application of polyurethane-acrylic ester fluorine-free water repellent agent disperse dye integrated product | 青岛大学 | 2025-05-06 | — | — | CN | disclosed |
| CN-119841720-A | Method for preparing tetramethyl cyclobutanedione | 中国石油化工股份有限公司 | 2025-04-18 | — | — | CN | disclosed |
| CN-119841720-A | Method for preparing tetramethyl cyclobutanedione | 中国石油化工股份有限公司 | 2025-04-18 | — | — | CN | disclosed |
| US-20240336868-A1 | COMPOSITIONS COMPRISING ADAMANTYL ESTER-CONTAINING COMPOUNDS | THE PROCTER & GAMBLE COMPANY | 2024-10-10 | — | — | US | disclosed |
| WO-2024147125-A1 | CYCLOBUTYL-SUBSTITUTED PHENOXY-DIOXETANES AND USES THEREOF | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2024-07-11 | — | — | WO | disclosed |
| US-4517379-A | ARTIFICIAL SWEETENER | PFIZER INC. (US) | 1985-05-14 | — | — | US | disclosed |
| EP-0069811-B1 | BRANCHED AMIDES OF L-ASPARTYL-D-AMINO ACID DIPEPTIDES AND COMPOSITIONS THEREOF | PFIZER INC. (US) | 1984-10-24 | — | — | EP | disclosed |
| EP-0034876-B1 | BRANCHED AMIDES OF L-ASPARTYL-D-AMINO ACID DIPEPTIDES AND COMPOSITIONS THEREOF | PFIZER INC. (US) | 1984-08-29 | — | — | EP | disclosed |
| US-4454328-A | SWEETENERS | PFIZER INC. (US) | 1984-06-12 | — | — | US | disclosed |
| US-4411925-A | STABLE SWEETENERS | PFIZER INC. (US) | 1983-10-25 | — | — | US | disclosed |
| US-4399163-A | ARTIFICIAL SWEETENERS | PFIZER INC. (US) | 1983-08-16 | — | — | US | disclosed |
| EP-0069811-A1 | Branched amides of L-aspartyl-D-amino acid dipeptides and compositions thereof | PFIZER INC. (US) | 1983-01-19 | — | — | EP | disclosed |