Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 7/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29933480 | 0.85 | SYK (0.49) | SYKHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL14659225 | 0.85 | SYK (0.49) | SYKHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL25156347 | 0.78 | CYP3A4 (0.58) | PDGFRBPDGFRAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30344821 | 0.78 | CYP3A4 (0.58) | PDGFRBPDGFRAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19616584 | 0.76 | CYP1A2 (0.40) | KDM4EMEN1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL29909876 | 0.76 | CYP1A2 (0.40) | KDM4EMEN1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL19617181 | 0.76 | HSP90AA1 (0.43) | HTR1AKDM4EMEN1TP53HSP90AA1 | |
| SCHEMBL25467033 | 0.72 | MAPT (0.45) | EGFRMEN1HTTKMT2ATDP1 | |
| SCHEMBL18318260 | 0.72 | ALDH1A1 (0.48) | SYKHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL30908153 | 0.72 | ALDH1A1 (0.48) | SYKHTR1AADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025040767-A1 | 2-(3,8-DIAZABICYCLO[3.2.1]OCTAN-3-YL)-1,3,5-TRIAZINE DERIVATIVES AS KRAS G12D INHIBITORS FOR THE TREATMENT OF CANCER | SANOFI (FR) | 2025-02-27 | — | — | WO | disclosed |